Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images

T. Berger, D. J. Noble, L. E. Shelley, T. McMullan, M. Romanchikova, L. J. Carruthers, L. Cebamanos, G. Beckett, A. Duffton, C. Paterson, R. Jena, D. B. McLaren, N. G. Burnet, W. H. Nailon

Research output: Contribution to journalMeeting abstractpeer-review

Abstract

There is a growing interest in predicting late xerostomia in head and neck (H&N) cancer patients using image biomarkers (IMBs) calculated on CT images acquired at
sparse intervals over the course of radiotherapy. In delivering radiotherapy with image guidance (IG) the TomoTherapy (Accuray, Sunnyvale, CA, USA) system allows
daily IG mega-voltage CT (MVCT) scans to be acquired with ease. The aim of this study was to 1) investigate whether changes in daily MVCT IMBs calculated on the parotid glands could predict late xerostomia (grade>1) and 2) establish the predictive power of the IMBs at different intervals of the radiotherapy course
Original languageEnglish
Pages (from-to)S859-S860
JournalRadiotherapy & Oncology
Volume152
Issue numberSupplement 1
DOIs
Publication statusE-pub ahead of print - 26 Nov 2020
EventEuropean Society for Radiotherapy and Oncology Conference 2020 - Vienna / Online, Austria
Duration: 28 Nov 20201 Dec 2020
https://www.estro.org/About/Newsroom/News/ESTRO-2020-New-concept,-new-dates

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