Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images

T. Berger; D. J.  Noble; L. E. Shelley; T. McMullan; M. Romanchikova; L. J. Carruthers; L. Cebamanos; G. Beckett; A. Duffton; C. Paterson; R. Jena; D. B. McLaren; N. G. Burnet; W. H. Nailon

doi:10.1016/S0167-8140(21)01602-9

Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images

T. Berger, D. J. Noble, L. E. Shelley, T. McMullan, M. Romanchikova, L. J. Carruthers, L. Cebamanos, G. Beckett, A. Duffton, C. Paterson, R. Jena, D. B. McLaren, N. G. Burnet, W. H. Nailon

Research output: Contribution to journal › Meeting abstract › peer-review

Abstract

There is a growing interest in predicting late xerostomia in head and neck (H&N) cancer patients using image biomarkers (IMBs) calculated on CT images acquired at
sparse intervals over the course of radiotherapy. In delivering radiotherapy with image guidance (IG) the TomoTherapy (Accuray, Sunnyvale, CA, USA) system allows
daily IG mega-voltage CT (MVCT) scans to be acquired with ease. The aim of this study was to 1) investigate whether changes in daily MVCT IMBs calculated on the parotid glands could predict late xerostomia (grade>1) and 2) establish the predictive power of the IMBs at different intervals of the radiotherapy course

Original language	English
Pages (from-to)	S859-S860
Journal	Radiotherapy & Oncology
Volume	152
Issue number	Supplement 1
DOIs	https://doi.org/10.1016/S0167-8140(21)01602-9
Publication status	E-pub ahead of print - 26 Nov 2020
Event	European Society for Radiotherapy and Oncology Conference 2020 - Vienna / Online, Austria Duration: 28 Nov 2020 → 1 Dec 2020 https://www.estro.org/About/Newsroom/News/ESTRO-2020-New-concept,-new-dates

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Berger, T., Noble, D. J., Shelley, L. E., McMullan, T., Romanchikova, M., Carruthers, L. J., Cebamanos, L., Beckett, G., Duffton, A., Paterson, C., Jena, R., McLaren, D. B., Burnet, N. G., & Nailon, W. H. (2020). Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images. Radiotherapy & Oncology, 152(Supplement 1), S859-S860. Advance online publication. https://doi.org/10.1016/S0167-8140(21)01602-9

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title = "Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images",

abstract = "There is a growing interest in predicting late xerostomia in head and neck (H&N) cancer patients using image biomarkers (IMBs) calculated on CT images acquired atsparse intervals over the course of radiotherapy. In delivering radiotherapy with image guidance (IG) the TomoTherapy (Accuray, Sunnyvale, CA, USA) system allowsdaily IG mega-voltage CT (MVCT) scans to be acquired with ease. The aim of this study was to 1) investigate whether changes in daily MVCT IMBs calculated on the parotid glands could predict late xerostomia (grade>1) and 2) establish the predictive power of the IMBs at different intervals of the radiotherapy course",

author = "T. Berger and Noble, {D. J.} and Shelley, {L. E.} and T. McMullan and M. Romanchikova and Carruthers, {L. J.} and L. Cebamanos and G. Beckett and A. Duffton and C. Paterson and R. Jena and McLaren, {D. B.} and Burnet, {N. G.} and Nailon, {W. H.}",

year = "2020",

month = nov,

day = "26",

doi = "10.1016/S0167-8140(21)01602-9",

language = "English",

volume = "152",

pages = "S859--S860",

journal = "Radiotherapy & Oncology",

issn = "0167-8140",

publisher = "Elsevier",

number = "Supplement 1",

note = "European Society for Radiotherapy and Oncology Conference 2020, ESTRO 2020 ; Conference date: 28-11-2020 Through 01-12-2020",

url = "https://www.estro.org/About/Newsroom/News/ESTRO-2020-New-concept,-new-dates",

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Berger, T, Noble, DJ, Shelley, LE, McMullan, T, Romanchikova, M, Carruthers, LJ, Cebamanos, L , Beckett, G, Duffton, A, Paterson, C, Jena, R, McLaren, DB, Burnet, NG & Nailon, WH 2020, 'Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images', Radiotherapy & Oncology, vol. 152, no. Supplement 1, pp. S859-S860. https://doi.org/10.1016/S0167-8140(21)01602-9

TY - JOUR

T1 - Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images

AU - Berger, T.

AU - Noble, D. J.

AU - Shelley, L. E.

AU - McMullan, T.

AU - Romanchikova, M.

AU - Carruthers, L. J.

AU - Cebamanos, L.

AU - Beckett, G.

AU - Duffton, A.

AU - Paterson, C.

AU - Jena, R.

AU - McLaren, D. B.

AU - Burnet, N. G.

AU - Nailon, W. H.

PY - 2020/11/26

Y1 - 2020/11/26

N2 - There is a growing interest in predicting late xerostomia in head and neck (H&N) cancer patients using image biomarkers (IMBs) calculated on CT images acquired atsparse intervals over the course of radiotherapy. In delivering radiotherapy with image guidance (IG) the TomoTherapy (Accuray, Sunnyvale, CA, USA) system allowsdaily IG mega-voltage CT (MVCT) scans to be acquired with ease. The aim of this study was to 1) investigate whether changes in daily MVCT IMBs calculated on the parotid glands could predict late xerostomia (grade>1) and 2) establish the predictive power of the IMBs at different intervals of the radiotherapy course

AB - There is a growing interest in predicting late xerostomia in head and neck (H&N) cancer patients using image biomarkers (IMBs) calculated on CT images acquired atsparse intervals over the course of radiotherapy. In delivering radiotherapy with image guidance (IG) the TomoTherapy (Accuray, Sunnyvale, CA, USA) system allowsdaily IG mega-voltage CT (MVCT) scans to be acquired with ease. The aim of this study was to 1) investigate whether changes in daily MVCT IMBs calculated on the parotid glands could predict late xerostomia (grade>1) and 2) establish the predictive power of the IMBs at different intervals of the radiotherapy course

U2 - 10.1016/S0167-8140(21)01602-9

DO - 10.1016/S0167-8140(21)01602-9

M3 - Meeting abstract

SN - 0167-8140

VL - 152

SP - S859-S860

JO - Radiotherapy & Oncology

JF - Radiotherapy & Oncology

IS - Supplement 1

T2 - European Society for Radiotherapy and Oncology Conference 2020

Y2 - 28 November 2020 through 1 December 2020

ER -

Predicting late xerostomia in head and neck cancer patients from imaging biomarkers calculated on daily TomoTherapy MVCT images

Abstract

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