Predicting susceptibility and incubation time of human-to-human transmission of vCJD

M T Bishop; Patricia Hart; L Aitchison; H N Baybutt; C Plinston; V Thomson; N L Tuzi; M W Head; J W Ironside; R G Will; J C Manson

doi:10.1016/S1474-4422(06)70413-6

Predicting susceptibility and incubation time of human-to-human transmission of vCJD

M T Bishop, Patricia Hart, L Aitchison, H N Baybutt, C Plinston, V Thomson, N L Tuzi, M W Head, J W Ironside, R G Will, J C Manson

Research output: Contribution to journal › Article › peer-review

Abstract

Identification of possible transmission of variant Creutzfeldt-Jakob disease (vCJD) via blood transfusion has caused concern over spread of the disease within the human population. We aimed to model iatrogenic spread to enable a comparison of transmission efficiencies of vCJD and bovine spongiform encephalopathy (BSE) and an assessment of the effect of the codon-129 polymorphism on human susceptibility.

Original language	English
Pages (from-to)	393-8
Number of pages	6
Journal	Lancet Neurology
Volume	5
Issue number	5
DOIs	https://doi.org/10.1016/S1474-4422(06)70413-6
Publication status	Published - 2006

Access to Document

10.1016/S1474-4422(06)70413-6

Cite this

@article{16382076b99d4b48a88c0fa3595d8361,

title = "Predicting susceptibility and incubation time of human-to-human transmission of vCJD",

abstract = "Identification of possible transmission of variant Creutzfeldt-Jakob disease (vCJD) via blood transfusion has caused concern over spread of the disease within the human population. We aimed to model iatrogenic spread to enable a comparison of transmission efficiencies of vCJD and bovine spongiform encephalopathy (BSE) and an assessment of the effect of the codon-129 polymorphism on human susceptibility.",

author = "Bishop, {M T} and Patricia Hart and L Aitchison and Baybutt, {H N} and C Plinston and V Thomson and Tuzi, {N L} and Head, {M W} and Ironside, {J W} and Will, {R G} and Manson, {J C}",

year = "2006",

doi = "10.1016/S1474-4422(06)70413-6",

language = "English",

volume = "5",

pages = "393--8",

journal = "Lancet Neurology",

issn = "1474-4422",

publisher = "ELSEVIER SCIENCE INC",

number = "5",

}

TY - JOUR

T1 - Predicting susceptibility and incubation time of human-to-human transmission of vCJD

AU - Bishop, M T

AU - Hart, Patricia

AU - Aitchison, L

AU - Baybutt, H N

AU - Plinston, C

AU - Thomson, V

AU - Tuzi, N L

AU - Head, M W

AU - Ironside, J W

AU - Will, R G

AU - Manson, J C

PY - 2006

Y1 - 2006

N2 - Identification of possible transmission of variant Creutzfeldt-Jakob disease (vCJD) via blood transfusion has caused concern over spread of the disease within the human population. We aimed to model iatrogenic spread to enable a comparison of transmission efficiencies of vCJD and bovine spongiform encephalopathy (BSE) and an assessment of the effect of the codon-129 polymorphism on human susceptibility.

AB - Identification of possible transmission of variant Creutzfeldt-Jakob disease (vCJD) via blood transfusion has caused concern over spread of the disease within the human population. We aimed to model iatrogenic spread to enable a comparison of transmission efficiencies of vCJD and bovine spongiform encephalopathy (BSE) and an assessment of the effect of the codon-129 polymorphism on human susceptibility.

U2 - 10.1016/S1474-4422(06)70413-6

DO - 10.1016/S1474-4422(06)70413-6

M3 - Article

C2 - 16632309

VL - 5

SP - 393

EP - 398

JO - Lancet Neurology

JF - Lancet Neurology

SN - 1474-4422

IS - 5

ER -

Predicting susceptibility and incubation time of human-to-human transmission of vCJD

Abstract

Access to Document

Fingerprint

Cite this