Projects per year
Photoperiod sensors allow physiological adaptation to the changing seasons. The prevalent hypothesis is that day length perception is mediated through coupling of an endogenous rhythm with an external light signal. Sufficient molecular data are available to test this quantitatively in plants, though not yet in mammals. In Arabidopsis, the clock-regulated genes CONSTANS (CO) and FLAVIN, KELCH, F-BOX (FKF1) and their light-sensitive proteins are thought to form an external coincidence sensor. Here, we model the integration of light and timing information by CO, its target gene FLOWERING LOCUS T (FT), and the circadian clock. Among other predictions, our models show that FKF1 activates FT. We demonstrate experimentally that this effect is independent of the known activation of CO by FKF1, thus we locate a major, novel controller of photoperiodism. External coincidence is part of a complex photoperiod sensor: modeling makes this complexity explicit and may thus contribute to crop improvement.
|Number of pages||10|
|Early online date||10 Dec 2009|
|Publication status||Published - 11 Dec 2009|
FingerprintDive into the research topics of 'Prediction of photoperiodic regulators from quantitative gene circuit models'. Together they form a unique fingerprint.
- 4 Finished
Regulation of biological signalling by temperature (ROBUST)
Halliday, K., Gilmore, S. & Millar, A.
14/04/08 → 13/10/13
SynthSys; formerly CSBE: Centre for Systems Biology at Edinburgh
Millar, A., Beggs, J., Ghazal, P., Goryanin, I., Hillston, J., Plotkin, G., Tollervey, D., Walton, A. & Robertson, K.
8/01/07 → 31/12/12
The role of phyB in the control of reproductive timing.
Halliday, K., Heggie, L., Yeung, J. & Salisbury, F. J.
1/10/05 → 31/10/07
- 1 Other contribution
Mathematical model of the Arabidopsis photoperiod sensor: Salazar 2009 modelSalazar, J. D., Saithong, T., Halliday, K., Rand, D. A. & Millar, A., 2009
Research output: Other contribution