Prediction of serum total antioxidant activity from the concentration of individual serum antioxidants

Simon R Maxwell, Thomas Dietrich, Iain L C Chapple

Research output: Contribution to journalArticlepeer-review

Abstract

Redox mechanisms are implicated in the pathogenesis of many diseases and several assays of total antioxidant capacity (TAOC) have been reported. Large epidemiological databases contain information on individual serum antioxidants as well as disease-specific phenotypic data. However, antioxidants work co-operatively in biological systems and it is important to be able to translate individual antioxidant measures into those of global antioxidant defence. Models therefore need developing to quantify contributions made by individual species to global antioxidant defence.
Original languageEnglish
Pages (from-to)188-94
Number of pages7
JournalClinica Chimica Acta
Volume372
Issue number1-2
DOIs
Publication statusPublished - 2006

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