Predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine-enhanced magnetic resonance imaging: diagnostic accuracy and confidence

Emilio Quaia; Roberta Angileri; Federica Arban; Antonio Giulio Gennari; Maria Assunta Cova

doi:10.1016/j.clinimag.2015.06.013

Predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine-enhanced magnetic resonance imaging: diagnostic accuracy and confidence

Emilio Quaia, Roberta Angileri, Federica Arban, Antonio Giulio Gennari, Maria Assunta Cova

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: To identify predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging.

METHODS: Fifty cirrhotic patients with 120 nodules, including 10 mass-forming intrahepatic cholangiocarcinomas and two combined hepatocellular carcinoma-cholangiocarcinomas, were scanned by Gd-BOPTA-enhanced MR imaging.

RESULTS: T1 hypointensity [odds ratio (OR), 20.12], peripheral hyperintense rim at hepatic arterial phase (OR, 13.5), and iso-hyperintensity at hepatobiliary phase (OR 21.32) were found to be independent predictors of intrahepatic cholangiocarcinoma.

CONCLUSIONS: T1 hypointensity, peripheral hyperintense rim at hepatic arterial phase, and iso-hyperintensity at hepatobiliary phase are independent predictors of intrahepatic cholangiocarcinoma diagnosis in patients with liver cirrhosis.

Original language	English
Pages (from-to)	1032-8
Number of pages	7
Journal	Clinical imaging
Volume	39
Issue number	6
DOIs	https://doi.org/10.1016/j.clinimag.2015.06.013
Publication status	Published - 19 Aug 2015

Keywords / Materials (for Non-textual outputs)

Adult
Aged
Aged, 80 and over
Bile Duct Neoplasms
Bile Ducts, Intrahepatic
Carcinoma, Hepatocellular
Case-Control Studies
Cholangiocarcinoma
Contrast Media
Female
Humans
Liver Cirrhosis
Liver Neoplasms
Magnetic Resonance Imaging
Male
Meglumine
Middle Aged
Organometallic Compounds
Retrospective Studies
Sensitivity and Specificity

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10.1016/j.clinimag.2015.06.013

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@article{be7fef2513ff4f0fbffd3181acc56902,

title = "Predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine-enhanced magnetic resonance imaging: diagnostic accuracy and confidence",

abstract = "OBJECTIVE: To identify predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging.METHODS: Fifty cirrhotic patients with 120 nodules, including 10 mass-forming intrahepatic cholangiocarcinomas and two combined hepatocellular carcinoma-cholangiocarcinomas, were scanned by Gd-BOPTA-enhanced MR imaging.RESULTS: T1 hypointensity [odds ratio (OR), 20.12], peripheral hyperintense rim at hepatic arterial phase (OR, 13.5), and iso-hyperintensity at hepatobiliary phase (OR 21.32) were found to be independent predictors of intrahepatic cholangiocarcinoma.CONCLUSIONS: T1 hypointensity, peripheral hyperintense rim at hepatic arterial phase, and iso-hyperintensity at hepatobiliary phase are independent predictors of intrahepatic cholangiocarcinoma diagnosis in patients with liver cirrhosis.",

keywords = "Adult, Aged, Aged, 80 and over, Bile Duct Neoplasms, Bile Ducts, Intrahepatic, Carcinoma, Hepatocellular, Case-Control Studies, Cholangiocarcinoma, Contrast Media, Female, Humans, Liver Cirrhosis, Liver Neoplasms, Magnetic Resonance Imaging, Male, Meglumine, Middle Aged, Organometallic Compounds, Retrospective Studies, Sensitivity and Specificity",

author = "Emilio Quaia and Roberta Angileri and Federica Arban and Gennari, {Antonio Giulio} and Cova, {Maria Assunta}",

year = "2015",

month = aug,

day = "19",

doi = "10.1016/j.clinimag.2015.06.013",

language = "English",

volume = "39",

pages = "1032--8",

journal = "Clinical imaging",

issn = "0899-7071",

publisher = "Elsevier",

number = "6",

}

TY - JOUR

T1 - Predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine-enhanced magnetic resonance imaging

T2 - diagnostic accuracy and confidence

AU - Quaia, Emilio

AU - Angileri, Roberta

AU - Arban, Federica

AU - Gennari, Antonio Giulio

AU - Cova, Maria Assunta

PY - 2015/8/19

Y1 - 2015/8/19

N2 - OBJECTIVE: To identify predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging.METHODS: Fifty cirrhotic patients with 120 nodules, including 10 mass-forming intrahepatic cholangiocarcinomas and two combined hepatocellular carcinoma-cholangiocarcinomas, were scanned by Gd-BOPTA-enhanced MR imaging.RESULTS: T1 hypointensity [odds ratio (OR), 20.12], peripheral hyperintense rim at hepatic arterial phase (OR, 13.5), and iso-hyperintensity at hepatobiliary phase (OR 21.32) were found to be independent predictors of intrahepatic cholangiocarcinoma.CONCLUSIONS: T1 hypointensity, peripheral hyperintense rim at hepatic arterial phase, and iso-hyperintensity at hepatobiliary phase are independent predictors of intrahepatic cholangiocarcinoma diagnosis in patients with liver cirrhosis.

AB - OBJECTIVE: To identify predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging.METHODS: Fifty cirrhotic patients with 120 nodules, including 10 mass-forming intrahepatic cholangiocarcinomas and two combined hepatocellular carcinoma-cholangiocarcinomas, were scanned by Gd-BOPTA-enhanced MR imaging.RESULTS: T1 hypointensity [odds ratio (OR), 20.12], peripheral hyperintense rim at hepatic arterial phase (OR, 13.5), and iso-hyperintensity at hepatobiliary phase (OR 21.32) were found to be independent predictors of intrahepatic cholangiocarcinoma.CONCLUSIONS: T1 hypointensity, peripheral hyperintense rim at hepatic arterial phase, and iso-hyperintensity at hepatobiliary phase are independent predictors of intrahepatic cholangiocarcinoma diagnosis in patients with liver cirrhosis.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Bile Duct Neoplasms

KW - Bile Ducts, Intrahepatic

KW - Carcinoma, Hepatocellular

KW - Case-Control Studies

KW - Cholangiocarcinoma

KW - Contrast Media

KW - Female

KW - Humans

KW - Liver Cirrhosis

KW - Liver Neoplasms

KW - Magnetic Resonance Imaging

KW - Male

KW - Meglumine

KW - Middle Aged

KW - Organometallic Compounds

KW - Retrospective Studies

KW - Sensitivity and Specificity

U2 - 10.1016/j.clinimag.2015.06.013

DO - 10.1016/j.clinimag.2015.06.013

M3 - Article

C2 - 26278014

SN - 0899-7071

VL - 39

SP - 1032

EP - 1038

JO - Clinical imaging

JF - Clinical imaging

IS - 6

ER -

Predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine-enhanced magnetic resonance imaging: diagnostic accuracy and confidence

Abstract

Keywords / Materials (for Non-textual outputs)

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