Predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine-enhanced magnetic resonance imaging: diagnostic accuracy and confidence

Emilio Quaia, Roberta Angileri, Federica Arban, Antonio Giulio Gennari, Maria Assunta Cova

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

OBJECTIVE: To identify predictors of intrahepatic cholangiocarcinoma in cirrhotic patients scanned by gadobenate dimeglumine (Gd-BOPTA)-enhanced magnetic resonance (MR) imaging.

METHODS: Fifty cirrhotic patients with 120 nodules, including 10 mass-forming intrahepatic cholangiocarcinomas and two combined hepatocellular carcinoma-cholangiocarcinomas, were scanned by Gd-BOPTA-enhanced MR imaging.

RESULTS: T1 hypointensity [odds ratio (OR), 20.12], peripheral hyperintense rim at hepatic arterial phase (OR, 13.5), and iso-hyperintensity at hepatobiliary phase (OR 21.32) were found to be independent predictors of intrahepatic cholangiocarcinoma.

CONCLUSIONS: T1 hypointensity, peripheral hyperintense rim at hepatic arterial phase, and iso-hyperintensity at hepatobiliary phase are independent predictors of intrahepatic cholangiocarcinoma diagnosis in patients with liver cirrhosis.

Original languageEnglish
Pages (from-to)1032-8
Number of pages7
JournalClinical imaging
Volume39
Issue number6
DOIs
Publication statusPublished - 19 Aug 2015

Keywords / Materials (for Non-textual outputs)

  • Adult
  • Aged
  • Aged, 80 and over
  • Bile Duct Neoplasms
  • Bile Ducts, Intrahepatic
  • Carcinoma, Hepatocellular
  • Case-Control Studies
  • Cholangiocarcinoma
  • Contrast Media
  • Female
  • Humans
  • Liver Cirrhosis
  • Liver Neoplasms
  • Magnetic Resonance Imaging
  • Male
  • Meglumine
  • Middle Aged
  • Organometallic Compounds
  • Retrospective Studies
  • Sensitivity and Specificity

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