Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy

Emilio Quaia*, Antonio Giulio Gennari, Luca De Paoli, Roberta Angileri, Maja Ukmar, Maria Assunta Cova

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To assess spectral presaturation inversion-recovery MRI sequence with gadolinium to identify predictors of mesorectal fascia (MRF) invasion in patients with locally advanced rectal carcinoma after neoadjuvant therapy. Materials and methods: Sixty-five patients underwent neoadjuvant concomitant radiation and chemotherapy and surgery. Magnetic resonance images were assessed by two radiologists. Results: Linear (odds ratio, 95% confidence intervals: 19.33, 1.98-188.6) and reticular strands (odds ratio, 95% confidence intervals: 9.75, 1.45-67.77) reaching the MRF are predictors of MRF invasion. Conclusion: Linear or reticular mesorectal strands reaching the MRF detected at contrast-enhanced MRI represent a predictor of MRF invasion.

Original languageEnglish
Pages (from-to)698-703
Number of pages6
JournalClinical imaging
Volume38
Issue number5
Early online date16 May 2014
DOIs
Publication statusPublished - Sep 2014
Externally publishedYes

Keywords

  • Magnetic resonance imaging
  • Mesorectal fascia
  • Neoadjuvant therapy
  • Rectal cancer

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