Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy

Emilio Quaia; Antonio Giulio Gennari; Luca De Paoli; Roberta Angileri; Maja Ukmar; Maria Assunta Cova

doi:10.1016/j.clinimag.2014.05.003

Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy

Emilio Quaia^*, Antonio Giulio Gennari, Luca De Paoli, Roberta Angileri, Maja Ukmar, Maria Assunta Cova

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Objective: To assess spectral presaturation inversion-recovery MRI sequence with gadolinium to identify predictors of mesorectal fascia (MRF) invasion in patients with locally advanced rectal carcinoma after neoadjuvant therapy. Materials and methods: Sixty-five patients underwent neoadjuvant concomitant radiation and chemotherapy and surgery. Magnetic resonance images were assessed by two radiologists. Results: Linear (odds ratio, 95% confidence intervals: 19.33, 1.98-188.6) and reticular strands (odds ratio, 95% confidence intervals: 9.75, 1.45-67.77) reaching the MRF are predictors of MRF invasion. Conclusion: Linear or reticular mesorectal strands reaching the MRF detected at contrast-enhanced MRI represent a predictor of MRF invasion.

Original language	English
Pages (from-to)	698-703
Number of pages	6
Journal	Clinical imaging
Volume	38
Issue number	5
Early online date	16 May 2014
DOIs	https://doi.org/10.1016/j.clinimag.2014.05.003
Publication status	Published - Sept 2014
Externally published	Yes

Keywords / Materials (for Non-textual outputs)

Magnetic resonance imaging
Mesorectal fascia
Neoadjuvant therapy
Rectal cancer

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10.1016/j.clinimag.2014.05.003

Cite this

@article{9dfc4f0afe764cfcbbe41b810c63aea7,

title = "Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy",

abstract = "Objective: To assess spectral presaturation inversion-recovery MRI sequence with gadolinium to identify predictors of mesorectal fascia (MRF) invasion in patients with locally advanced rectal carcinoma after neoadjuvant therapy. Materials and methods: Sixty-five patients underwent neoadjuvant concomitant radiation and chemotherapy and surgery. Magnetic resonance images were assessed by two radiologists. Results: Linear (odds ratio, 95% confidence intervals: 19.33, 1.98-188.6) and reticular strands (odds ratio, 95% confidence intervals: 9.75, 1.45-67.77) reaching the MRF are predictors of MRF invasion. Conclusion: Linear or reticular mesorectal strands reaching the MRF detected at contrast-enhanced MRI represent a predictor of MRF invasion.",

keywords = "Magnetic resonance imaging, Mesorectal fascia, Neoadjuvant therapy, Rectal cancer",

author = "Emilio Quaia and Gennari, {Antonio Giulio} and {De Paoli}, Luca and Roberta Angileri and Maja Ukmar and Cova, {Maria Assunta}",

year = "2014",

month = sep,

doi = "10.1016/j.clinimag.2014.05.003",

language = "English",

volume = "38",

pages = "698--703",

journal = "Clinical imaging",

issn = "0899-7071",

publisher = "Elsevier",

number = "5",

}

TY - JOUR

T1 - Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy

AU - Quaia, Emilio

AU - Gennari, Antonio Giulio

AU - De Paoli, Luca

AU - Angileri, Roberta

AU - Ukmar, Maja

AU - Cova, Maria Assunta

PY - 2014/9

Y1 - 2014/9

N2 - Objective: To assess spectral presaturation inversion-recovery MRI sequence with gadolinium to identify predictors of mesorectal fascia (MRF) invasion in patients with locally advanced rectal carcinoma after neoadjuvant therapy. Materials and methods: Sixty-five patients underwent neoadjuvant concomitant radiation and chemotherapy and surgery. Magnetic resonance images were assessed by two radiologists. Results: Linear (odds ratio, 95% confidence intervals: 19.33, 1.98-188.6) and reticular strands (odds ratio, 95% confidence intervals: 9.75, 1.45-67.77) reaching the MRF are predictors of MRF invasion. Conclusion: Linear or reticular mesorectal strands reaching the MRF detected at contrast-enhanced MRI represent a predictor of MRF invasion.

AB - Objective: To assess spectral presaturation inversion-recovery MRI sequence with gadolinium to identify predictors of mesorectal fascia (MRF) invasion in patients with locally advanced rectal carcinoma after neoadjuvant therapy. Materials and methods: Sixty-five patients underwent neoadjuvant concomitant radiation and chemotherapy and surgery. Magnetic resonance images were assessed by two radiologists. Results: Linear (odds ratio, 95% confidence intervals: 19.33, 1.98-188.6) and reticular strands (odds ratio, 95% confidence intervals: 9.75, 1.45-67.77) reaching the MRF are predictors of MRF invasion. Conclusion: Linear or reticular mesorectal strands reaching the MRF detected at contrast-enhanced MRI represent a predictor of MRF invasion.

KW - Magnetic resonance imaging

KW - Mesorectal fascia

KW - Neoadjuvant therapy

KW - Rectal cancer

UR - http://www.scopus.com/inward/record.url?scp=84906054919&partnerID=8YFLogxK

U2 - 10.1016/j.clinimag.2014.05.003

DO - 10.1016/j.clinimag.2014.05.003

M3 - Article

C2 - 24934670

AN - SCOPUS:84906054919

SN - 0899-7071

VL - 38

SP - 698

EP - 703

JO - Clinical imaging

JF - Clinical imaging

IS - 5

ER -

Predictors of mesorectal fascia invasion after gadolinium injection in rectal carcinoma after neoadjuvant therapy

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Keywords / Materials (for Non-textual outputs)

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