PREPARE: guidelines for planning animal research and testing

Adrian J Smith, R Eddie Clutton, Elliot Lilley, Kristine E Aa Hansen, Trond Brattelid

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

There is widespread concern about the quality, reproducibility and translatability of studies involving research animals. Although there are a number of reporting guidelines available, there is very little overarching guidance on how to plan animal experiments, despite the fact that this is the logical place to start ensuring quality. In this paper we present the PREPARE guidelines: Planning Research and Experimental Procedures on Animals: Recommendations for Excellence. PREPARE covers the three broad areas which determine the quality of the preparation for animal studies: formulation, dialogue between scientists and the animal facility, and quality control of the various components in the study. Some topics overlap and the PREPARE checklist should be adapted to suit specific needs, for example in field research. Advice on use of the checklist is available on the Norecopa website, with links to guidelines for animal research and testing, at .

Original languageEnglish
Pages (from-to)135-141
JournalLaboratory Animals
Issue number2
Early online date3 Aug 2017
Publication statusPublished - Apr 2018

Keywords / Materials (for Non-textual outputs)

  • Journal Article


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