Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease

Salvatore Rudilosso; Ernest Chui; Michael S Stringer; Michael Thrippleton; Francesca Chappell; Gordon Blair; Daniela Jaime Garcãa; Fergus Doubal; Iona Hamilton; Anna Kopczak; Michael Ingrish; Danielle Kerkhofs; Walter H Backes; Julie Staals; Robert Van Oostenbrugge; Marco Duering; Martin Dichgans; Joanna M. Wardlaw

doi:10.1212/WNL.0000000000200614

Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease

Salvatore Rudilosso, Ernest Chui, Michael S Stringer, Michael Thrippleton, Francesca Chappell, Gordon Blair, Daniela Jaime Garcãa, Fergus Doubal, Iona Hamilton, Anna Kopczak, Michael Ingrish, Danielle Kerkhofs, Walter H Backes, Julie Staals, Robert Van Oostenbrugge, Marco Duering, Martin Dichgans, Joanna M. Wardlaw

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	10.1212/WNL.0000000000200614
Journal	Neurology
Early online date	23 May 2022
DOIs	https://doi.org/10.1212/WNL.0000000000200614
Publication status	E-pub ahead of print - 23 May 2022

Access to Document

10.1212/WNL.0000000000200614

WNL.0000000000200614.fullAccepted author manuscript, 3.27 MBLicence: Creative Commons: Attribution (CC-BY)

http://www.neurology.org/lookup/doi/10.1212/WNL.0000000000200614

Cite this

Rudilosso, S., Chui, E., Stringer, M. S., Thrippleton, M., Chappell, F., Blair, G., Garcãa, D. J., Doubal, F., Hamilton, I., Kopczak, A., Ingrish, M., Kerkhofs, D., Backes, W. H., Staals, J., Van Oostenbrugge, R., Duering, M., Dichgans, M., & Wardlaw, J. M. (2022). Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease. Neurology, 10.1212/WNL.0000000000200614. https://doi.org/10.1212/WNL.0000000000200614

@article{0fc249119f654c059e9386d07a459380,

title = "Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease",

author = "Salvatore Rudilosso and Ernest Chui and Stringer, {Michael S} and Michael Thrippleton and Francesca Chappell and Gordon Blair and Garc{\~a}a, {Daniela Jaime} and Fergus Doubal and Iona Hamilton and Anna Kopczak and Michael Ingrish and Danielle Kerkhofs and Backes, {Walter H} and Julie Staals and {Van Oostenbrugge}, Robert and Marco Duering and Martin Dichgans and Wardlaw, {Joanna M.}",

note = "Funding Information: The Article Processing Charge was funded by Research Council of United Kingdom. Funding Information: SR receives funding from Instituto de Salud Carlos III, with a grant for health research and a mobility grant (CM18/00116; RH041992). INVESTIGATE@SVDs is funded by the European Union Horizon 2020, PHC-03-15, Project No. 666881, “SVDs@Target{\textquoteright}. This study was also supported by the Fondation Leducq Transatlantic Network of Excellence for the Study of Perivascular Spaces in Small Vessel Disease, Ref. No. 16 CVD 05: The Row Fogo Charitable Trust; The Row Fogo Centre for Research into Ageing and the Brain, Ref. No.: AD.ROW4.35. BRO-D.FID3668413; the Stroke Association Princess Margaret Research Development Fellowship scheme (GWB); the Stroke Association Garfield Weston Foundation Senior Clinical Lectureship and NHS Research Scotland (FND); the NHS Lothian Research and Development Office (MJT); the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK Medical Research Council, Alzheimer's Society and Alzheimer's Research UK; and the Edinburgh 3T MRI scanner is funded by the Wellcome Trust (104916/Z/14/Z), Dunhill Trust (R380R/1114), the Edinburgh and Lothians Health Foundation (2012/17), the Muir Maxwell Research Fund, and the University of Edinburgh. The procurement of the MRI scanner in Munich was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) grant for major research instrumentation (DFG, INST 409/193-1 FUGG). Publisher Copyright: {\textcopyright} American Academy of Neurology.",

year = "2022",

month = may,

day = "23",

doi = "10.1212/WNL.0000000000200614",

language = "English",

pages = "10.1212/WNL.0000000000200614",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

}

Rudilosso, S, Chui, E, Stringer, MS , Thrippleton, M , Chappell, F, Blair, G, Garcãa, DJ, Doubal, F, Hamilton, I, Kopczak, A, Ingrish, M, Kerkhofs, D, Backes, WH, Staals, J, Van Oostenbrugge, R, Duering, M, Dichgans, M & Wardlaw, JM 2022, 'Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease', Neurology, pp. 10.1212/WNL.0000000000200614. https://doi.org/10.1212/WNL.0000000000200614

TY - JOUR

T1 - Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease

AU - Rudilosso, Salvatore

AU - Chui, Ernest

AU - Stringer, Michael S

AU - Thrippleton, Michael

AU - Chappell, Francesca

AU - Blair, Gordon

AU - Garcãa, Daniela Jaime

AU - Doubal, Fergus

AU - Hamilton, Iona

AU - Kopczak, Anna

AU - Ingrish, Michael

AU - Kerkhofs, Danielle

AU - Backes, Walter H

AU - Staals, Julie

AU - Van Oostenbrugge, Robert

AU - Duering, Marco

AU - Dichgans, Martin

AU - Wardlaw, Joanna M.

N1 - Funding Information: The Article Processing Charge was funded by Research Council of United Kingdom. Funding Information: SR receives funding from Instituto de Salud Carlos III, with a grant for health research and a mobility grant (CM18/00116; RH041992). INVESTIGATE@SVDs is funded by the European Union Horizon 2020, PHC-03-15, Project No. 666881, “SVDs@Target’. This study was also supported by the Fondation Leducq Transatlantic Network of Excellence for the Study of Perivascular Spaces in Small Vessel Disease, Ref. No. 16 CVD 05: The Row Fogo Charitable Trust; The Row Fogo Centre for Research into Ageing and the Brain, Ref. No.: AD.ROW4.35. BRO-D.FID3668413; the Stroke Association Princess Margaret Research Development Fellowship scheme (GWB); the Stroke Association Garfield Weston Foundation Senior Clinical Lectureship and NHS Research Scotland (FND); the NHS Lothian Research and Development Office (MJT); the UK Dementia Research Institute which receives its funding from DRI Ltd, funded by the UK Medical Research Council, Alzheimer's Society and Alzheimer's Research UK; and the Edinburgh 3T MRI scanner is funded by the Wellcome Trust (104916/Z/14/Z), Dunhill Trust (R380R/1114), the Edinburgh and Lothians Health Foundation (2012/17), the Muir Maxwell Research Fund, and the University of Edinburgh. The procurement of the MRI scanner in Munich was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) grant for major research instrumentation (DFG, INST 409/193-1 FUGG). Publisher Copyright: © American Academy of Neurology.

PY - 2022/5/23

Y1 - 2022/5/23

U2 - 10.1212/WNL.0000000000200614

DO - 10.1212/WNL.0000000000200614

M3 - Article

SP - 10.1212/WNL.0000000000200614

JO - Neurology

JF - Neurology

SN - 0028-3878

ER -