Prevalence of the group 1 Dermatophagoides allergens Der p 1 and Der f 1 in homes with no dogs, healthy dogs and Dermatophagoides-sensitized atopic dogs in Liverpool

Eleanor Raffan, Helen Lawrence, Thomas Henderson, Sarah Nelson, Diana Isherwood, Claire McArdle, Tim Nuttall

Research output: Contribution to journalArticlepeer-review

Abstract

Dermatophagoides farinae is a frequent allergen in canine atopic dermatitis despite its reported scarcity in the UK, and the aim of this study was to determine whether dogs were uniquely exposed to this species. Der f 1 and Der p 1 in dust collected from living room carpets, bedroom carpets and dog beds of 13 houses with no dogs, 13 with healthy dogs, and 16 with Dermatophagoides-sensitized atopic dogs were quantified by ELISA. Der p 1 levels (microg g(-1) house dust) were significantly higher than Der f 1 in living rooms (Der p 1 median = 1.9, 95% CI = 2.05-6.32, n = 42; Der f 1 median = 0.07, 95% CI = 0.01-0.06, n = 42), bedrooms (Der p 1 median = 4.35, SD = 5.52; Der f 1 median = 0.01, 95% CI = 0.001-0.1, n = 42) and dog beds (Der p 1 median = 1.04, 95% CI = 1.4-8.1, n = 29; Der f 1 median = 0.008, 95% CI = 0.01-0.04, n = 29) (P
Original languageEnglish
Pages (from-to)253-60
Number of pages8
JournalVeterinary Dermatology
Volume16
Issue number4
DOIs
Publication statusPublished - Aug 2005

Keywords

  • Animals
  • Antigens, Dermatophagoides
  • Arthropod Proteins
  • Case-Control Studies
  • Cysteine Endopeptidases
  • Dermatitis, Atopic
  • Dog Diseases
  • Dogs
  • Dust
  • England
  • Housing, Animal
  • Prevalence

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