Prevalence of tuberculous lesion in cattle slaughtered in Mubende district, Uganda

Daniel Pakasi Nalapa, Adrian Muwonge, Clovice Kankya, Francisco Olea-Popelka

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Abstract

Background: The aim of this study was to estimate the prevalence and risk factors associated with the presence of gross pathology suggestive of bovine tuberculosis (Tuberculosis (TB) -like lesions) among cattle slaughtered in Mubende district in the Uganda cattle corridor.

Method: We conducted a cross sectional study in which 1,576 slaughtered cattle in Mubende district underwent post-mortem inspection between August 2013 and January 2014. Tissue samples were collected from all carcases that had bovine TB-like lesions in addition to the animal’s gender, age, breed, and origin information. The tissues were processed using standard Mycobacterium culture and identification methods. The culture and acid fast positive samples were tested using Capilia TB-neo® assay to identify Mycobacterium tuberculosis complex (MTC). Age, gender, breed, and animal origin were evaluated using a chi square test, multivariable and exact logistic regression models to assess if these factors were associated with presence of bovine TB-like lesions and genus mycobacterium in slaughter cattle in slaughter cattle respectively in R-studio 3.03.

Results: Of 1,576 carcasses inspected, 9.7% (153/1,576) had bovine TB-like lesions from which Mycobacterium spp and MTC were isolated in 13 (8.4%) and 12 (7.8%) respectively. TB-like lesions were most likely to be observed in females (OR=1.49, OR 95% CI: 1.06, 2.13) and in old cattle (OR=2.5, 95% CI: 1.64, 3.7), When compared to Ankole cattle, Cross breed (OR=6.5, OR 95% CI: 3.37, 12.7) and Zebu cattle (OR=2.57, 95% CI: 1.78, 3.72) had higher odds of presenting with bovine-TB like lesions. Animal from Kasambya (OR=2.5, 95% CI: 1.52, 4.17) were more likely to disclose bovine TB-like lesions than cattle from Kasambya. MTC was identified in 8.4% of the bovine TB-like lesion.

Conclusions: The findings in study reveals that one in ten slaughtered cattle presents with gross pathology suggestive of bovine TB (TB-like lesions) in Mubende district in the Uganda cattle corridor district, however, we identified MTC in only 8.4% of these TB-like lesions. Therefore, there is need to understand the cause of all the other bovine TB-like lesions in order to safe guard diagnostic integrity of meat inspection in Uganda.
Original languageEnglish
Article number73
Number of pages8
JournalBMC Veterinary Research
Volume13
Issue number1
Early online date21 Mar 2017
DOIs
Publication statusE-pub ahead of print - 21 Mar 2017

Keywords

  • Tuberculous –like lesions
  • Uganda cattle corridor
  • bovine tuberculosis

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