Preventing Cognitive Decline and Dementia from Cerebral Small Vessel Disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination

Gordon Blair
, Jason P Appleton
, Zhe Kang Law
, Fergus Doubal
, Katie Flaherty
, Richard Dooley
, Kirsten Shuler
, Carla Richardson
, Iona Hamilton
, Yulu Shi
, Michael Stringer
, Julia Boyd
, Michael Thrippleton
, Nikola Sprigg
, Philip M Bath
, Joanna Wardlaw

Research output: Contribution to journal › Article › peer-review

6 results

Finished
Understanding the Role of the Perivascular Space in Cerebral Small Vessel Disease
Wardlaw, J. (Principal Investigator)
1/01/17 → 31/12/23
Project: Research
SVDs-at-target: Small vessel diseases in a mechanistic perspective: Targets for Intervention Affected pathways and mechanistic exploitation for prevention of stroke and dementia
Wardlaw, J. (Principal Investigator)
EU government bodies
1/01/16 → 31/12/21
Project: Research
Preventing cognitive decline and dementia from cerebral microvascular disease
Wardlaw, J. (Principal Investigator) & Thrippleton, M. (Co-investigator)
UK-based charities
1/10/15 → 31/07/18
Project: Research
Senior Clinical Lectureship: A platform for patient focused trials to prevent cerebral small vessel disease
Doubal, F. (Principal Investigator)
UK-based charities
1/06/15 → 31/05/21
Project: Research
Right-2 Imaging Resources - Rapid Intervention With Glyceryl Trinitrate In Hypertensive Stroke Trial-2 (Right-2)
Wardlaw, J. (Principal Investigator)
Other
1/05/15 → 31/10/18
Project: Research
Scottish Imaging Network : A Platform for Scientific Excellence (SINAPSE)
Wardlaw, J. (Principal Investigator)
UK central government bodies/local authorities, health and hospital authorities
1/08/07 → 31/12/14
Project: Research