Abstract
Primary progressive aphasia (PPA) is a neurodegenerative disorder affecting language and communication functions. PPA symptoms usually have an insidious onset and get worse over time. Non-linguistic cognitive functions remain preserved until the late stages of progression, showing that PPA has to be differentiated from other diseases such as Alzheimer's disease. Patient studies revealed a great heterogeneity within PPA. Further research based on clinical and pathophysiological markers could distinguish between three PPA variants (semantic, nonfl uent/agrammatic and logopenic variant of PPA). This article reviews current research about the clinical manifestations of the three different PPA variants. Furthermore, we provide a case study of a PPA patient and an overview of recommended tasks for differential diagnostic purposes.
| Translated title of the contribution | Primary progressive aphasia: An overview |
|---|---|
| Original language | German |
| Pages (from-to) | 26-32 |
| Number of pages | 7 |
| Journal | Forum Logopadie |
| Volume | 29 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 May 2015 |
Keywords / Materials (for Non-textual outputs)
- Agrammatism
- Apraxia of speech
- Dementia
- Neurodegenerative disorder
- Primary progressive aphasia
- Semantic dementia