Primär progrediente aphasien -Übersicht, klinisches erscheinungsbild und kompensatorische maßnahmen

Translated title of the contribution: Primary progressive aphasia: An overview

Lisa Marie Rutter, Thomas H. Bak*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Primary progressive aphasia (PPA) is a neurodegenerative disorder affecting language and communication functions. PPA symptoms usually have an insidious onset and get worse over time. Non-linguistic cognitive functions remain preserved until the late stages of progression, showing that PPA has to be differentiated from other diseases such as Alzheimer's disease. Patient studies revealed a great heterogeneity within PPA. Further research based on clinical and pathophysiological markers could distinguish between three PPA variants (semantic, nonfl uent/agrammatic and logopenic variant of PPA). This article reviews current research about the clinical manifestations of the three different PPA variants. Furthermore, we provide a case study of a PPA patient and an overview of recommended tasks for differential diagnostic purposes.

Translated title of the contributionPrimary progressive aphasia: An overview
Original languageGerman
Pages (from-to)26-32
Number of pages7
JournalForum Logopadie
Issue number3
Publication statusPublished - 1 May 2015

Keywords / Materials (for Non-textual outputs)

  • Agrammatism
  • Apraxia of speech
  • Dementia
  • Neurodegenerative disorder
  • Primary progressive aphasia
  • Semantic dementia


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