Probing the substrate specificity of the catalytically self-sufficient cytochrome P450 RhF from a Rhodococcus sp

Ayhan Celik, Gareth A Roberts, John H White, Stephen K Chapman, Nicholas J Turner, Sabine L Flitsch

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Analysis of the substrate specificity of the self-sufficient cytochrome P450 RhF revealed that the enzyme tends to catalyse the dealkylation of substituted alkyl-aryl ethers with shorter alkyl moieties more readily than equivalent compounds with longer alkyl groups.

Original languageEnglish
Pages (from-to)4492-4
Number of pages3
JournalChemical Communications
Issue number43
DOIs
Publication statusPublished - 14 Sept 2006

Keywords / Materials (for Non-textual outputs)

  • Alkylation
  • Catalysis
  • Cytochrome P-450 Enzyme System/metabolism
  • Ethers/metabolism
  • Rhodococcus
  • Substrate Specificity

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