Processing of pre‐ribosomal RNA in Saccharomyces cerevisiae

Jaap Venema, David Tollervey*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Post‐transcriptional processing of precursor‐ribosomal RNA comprises a complex pathway of endonucleolytic cleavages, exonucleolytic digestion and covalent modifications. The general order of the various processing steps is well conserved in eukaryotic cells, but the underlying mechanisms are largely unknown. Recent analysis of pre‐rRNA processing, mainly in the yeast Saccharomyces cerevisiae, has significantly improved our understanding of this important cellular activity. Here we will review the data that have led to our current picture of yeast pre‐rRNA processing.

Original languageEnglish
Pages (from-to)1629-1650
Number of pages22
JournalYeast
Volume11
Issue number16
DOIs
Publication statusPublished - Dec 1995

Keywords

  • assembly
  • nuclease
  • ribosome
  • RNA processing
  • snoRNA
  • snoRNP
  • yeast

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