Prognostic value of single-photon emission tomography in acute ischaemic stroke

CJ Weir, AA Bolster, S Tytler, GD Murray, RS Corrigall, FG Adams, KR Lees

Research output: Contribution to journalArticlepeer-review

Abstract

Single-photon emission tomography (SPET) is widely used in the investigation of acute stroke. We investigated the relationship between SPET data and functional outcome in a large group of acute stroke patients. One hundred and eight patients underwent cerebral computed tomography (CT) and technetium-99m hexamethylpropylene amine oxime SPET after acute ischaemic stroke. We categorised the clinical presentation according to the Oxford classification of acute stroke. Outcome was measured 1 year after stroke using mortality and the Barthel Index for survivors. SPET scans were interpreted without reference to the clinical data using a semi-automatic technique. Three experienced observers determined the presence of luxury perfusion using suitably scaled SPET images in conjunction with the CT scan. Both SPET volume and severity of deficit were significantly negatively correlated with Barthel Index at 1 year (r(s)=-0.310, P

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalEuropean journal of nuclear medicine
Volume24
Issue number1
Publication statusPublished - Jan 1997

Keywords

  • single-photon emission tomography
  • stroke outcome
  • cerebral infarction
  • CEREBRAL BLOOD-FLOW
  • ACUTE ISCHEMIC STROKE
  • COMPUTED-TOMOGRAPHY
  • CEREBROVASCULAR-DISEASE
  • PREDICTIVE VALUE
  • BRAIN RECOVERY
  • SPECT
  • INFARCTION
  • PERFUSION
  • SCORE

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