Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

Stefania Segditsas; Oliver M. Sieber; Andrew Rowan; Fernando Setien; Kay Neale; Robin K.s. Phillips; Robyn Ward; Manel Esteller; Ian P.m. Tomlinson

doi:10.1016/j.yexmp.2008.09.006

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

Stefania Segditsas, Oliver M. Sieber, Andrew Rowan, Fernando Setien, Kay Neale, Robin K.s. Phillips, Robyn Ward, Manel Esteller, Ian P.m. Tomlinson

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	201-206
Journal	Experimental and Molecular Pathology
Volume	85
Issue number	3
DOIs	https://doi.org/10.1016/j.yexmp.2008.09.006
Publication status	Published - 1 Dec 2008

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10.1016/j.yexmp.2008.09.006

https://linkinghub.elsevier.com/retrieve/pii/S0014480008001093

Cite this

Segditsas, S., Sieber, O. M., Rowan, A., Setien, F., Neale, K., Phillips, R. K. S., Ward, R., Esteller, M., & Tomlinson, I. P. M. (2008). Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations. Experimental and Molecular Pathology, 85(3), 201-206. https://doi.org/10.1016/j.yexmp.2008.09.006

Segditsas, Stefania ; Sieber, Oliver M. ; Rowan, Andrew ; Setien, Fernando ; Neale, Kay ; Phillips, Robin K.s. ; Ward, Robyn ; Esteller, Manel ; Tomlinson, Ian P.m. / Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations. In: Experimental and Molecular Pathology. 2008 ; Vol. 85, No. 3. pp. 201-206.

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title = "Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations",

author = "Stefania Segditsas and Sieber, {Oliver M.} and Andrew Rowan and Fernando Setien and Kay Neale and Phillips, {Robin K.s.} and Robyn Ward and Manel Esteller and Tomlinson, {Ian P.m.}",

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Segditsas, S, Sieber, OM, Rowan, A, Setien, F, Neale, K, Phillips, RKS, Ward, R, Esteller, M & Tomlinson, IPM 2008, 'Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations', Experimental and Molecular Pathology, vol. 85, no. 3, pp. 201-206. https://doi.org/10.1016/j.yexmp.2008.09.006

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations. / Segditsas, Stefania; Sieber, Oliver M.; Rowan, Andrew; Setien, Fernando; Neale, Kay; Phillips, Robin K.s.; Ward, Robyn; Esteller, Manel; Tomlinson, Ian P.m.

In: Experimental and Molecular Pathology, Vol. 85, No. 3, 01.12.2008, p. 201-206.

Research output: Contribution to journal › Article › peer-review

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T1 - Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations

AU - Segditsas, Stefania

AU - Sieber, Oliver M.

AU - Rowan, Andrew

AU - Setien, Fernando

AU - Neale, Kay

AU - Phillips, Robin K.s.

AU - Ward, Robyn

AU - Esteller, Manel

AU - Tomlinson, Ian P.m.

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