Proposal for rational antibacterials use in the diagnosis and treatment of dogs with chronic diarrhoea

Matteo Cerquetella, Giacomo Rossi , Jan Suchodolski, Silke Salavati, Karin Allenspach, Fernando Rodriguez-Franco , Tommaso Furlanello , Alessandra Gavazza, Andrea Marchegiani, Stefan Unterer, Iwan A. Burgener, Graziano Pengo , A. E. Jergens

Research output: Contribution to journalArticlepeer-review


Chronic diarrhoea is a frequent complaint in canine practice, and the diagnostic path is often characterized by numerous diagnostic tests and stepwise empirical treatments, often performed prior to gastrointestinal endoscopy/mucosal biopsies. These include dietary interventions (novel protein/hydrolysed protein diet), parasiticides and, still, in many cases, antibacterials. In order to decrease the risk of multiple potentially detrimental consequences for both the individual patient (antimicrobial resistance, long-term disruption of intestinal bacterial populations, potential worsening of gastrointestinal signs) and the general public, we advocate the use of antibacterials only after histopathologic evaluation of gastrointestinal biopsies, or at least after that any other therapeutic trial (e.g. diet/pre-probiotics, anti-inflammatory drugs) has been shown to be unsuccessful, in those cases in which endoscopy is not possible. They should be reserved, after appropriate dietary trials, for those canine chronic diarrhoeic patients with signs of true primary infection (signs of systemic inflammatory response syndrome or evidence of adherent-invasive bacteria) that justify antibacterial usage. In the present article we therefore discourage the empirical use of antibacterials when managing dogs with suspected chronic enteropathy.

Original languageEnglish
JournalJournal of Small Animal Practice
Early online date17 Feb 2020
Publication statusE-pub ahead of print - 17 Feb 2020


  • dog
  • antibacterials/antibiotics
  • chronic enteropathy
  • diagnosis
  • therapy


Dive into the research topics of 'Proposal for rational antibacterials use in the diagnosis and treatment of dogs with chronic diarrhoea'. Together they form a unique fingerprint.

Cite this