Pulmonary embolism diagnosis: clinical assessment at the front door

John Cafferkey; Philippa Serebriakoff; Kerstin de Wit; Daniel E Horner; Matthew James Reed

doi:10.1136/emermed-2021-212000

Pulmonary embolism diagnosis: clinical assessment at the front door

John Cafferkey, Philippa Serebriakoff, Kerstin de Wit, Daniel E Horner, Matthew James Reed

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

This first of two practice reviews addresses pulmonary embolism (PE) diagnosis considering important aspects of PE clinical presentation and comparing evidence-based PE testing strategies. A companion paper addresses the management of PE. Symptoms and signs of PE are varied, and emergency physicians frequently use testing to 'rule out' the diagnosis in people with respiratory or cardiovascular symptoms. The emergency clinician must balance the benefit of reassuring negative PE testing with the risks of iatrogenic harms from over investigation and overdiagnosis.

Original language	English
Article number	emermed-2021-212000
Pages (from-to)	945-951
Journal	Emergency Medicine Journal
Volume	39
Issue number	12
Early online date	22 Jul 2022
DOIs	https://doi.org/10.1136/emermed-2021-212000
Publication status	Published - 22 Nov 2022

Keywords / Materials (for Non-textual outputs)

diagnosis
emergency care systems
pulmonary embolism
thrombo-embolic disease

Access to Document

10.1136/emermed-2021-212000

Paper 1 final accepted paper for PUREAccepted author manuscript, 797 KBLicence: Creative Commons: Attribution Non-Commercial (CC-BY-NC)

Cite this

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title = "Pulmonary embolism diagnosis: clinical assessment at the front door",

abstract = "This first of two practice reviews addresses pulmonary embolism (PE) diagnosis considering important aspects of PE clinical presentation and comparing evidence-based PE testing strategies. A companion paper addresses the management of PE. Symptoms and signs of PE are varied, and emergency physicians frequently use testing to 'rule out' the diagnosis in people with respiratory or cardiovascular symptoms. The emergency clinician must balance the benefit of reassuring negative PE testing with the risks of iatrogenic harms from over investigation and overdiagnosis.",

keywords = "diagnosis, emergency care systems, pulmonary embolism, thrombo-embolic disease",

author = "John Cafferkey and Philippa Serebriakoff and {de Wit}, Kerstin and Horner, {Daniel E} and Reed, {Matthew James}",

note = "Funding Information: The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. No funding was used for the preparation of this manuscript. MJR is currently appointed as professor of the Royal College of Emergency Medicine and is supported by an NHS Research Scotland Career Researcher Clinician award. DEH has specific NIHR funding relevant to a thrombosis research project (NIHR127454). Publisher Copyright: {\textcopyright} Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.",

year = "2022",

month = nov,

day = "22",

doi = "10.1136/emermed-2021-212000",

language = "English",

volume = "39",

pages = "945--951",

journal = "Emergency Medicine Journal",

issn = "1472-0205",

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TY - JOUR

T1 - Pulmonary embolism diagnosis

T2 - clinical assessment at the front door

AU - Cafferkey, John

AU - Serebriakoff, Philippa

AU - de Wit, Kerstin

AU - Horner, Daniel E

AU - Reed, Matthew James

N1 - Funding Information: The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. No funding was used for the preparation of this manuscript. MJR is currently appointed as professor of the Royal College of Emergency Medicine and is supported by an NHS Research Scotland Career Researcher Clinician award. DEH has specific NIHR funding relevant to a thrombosis research project (NIHR127454). Publisher Copyright: © Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2022/11/22

Y1 - 2022/11/22

N2 - This first of two practice reviews addresses pulmonary embolism (PE) diagnosis considering important aspects of PE clinical presentation and comparing evidence-based PE testing strategies. A companion paper addresses the management of PE. Symptoms and signs of PE are varied, and emergency physicians frequently use testing to 'rule out' the diagnosis in people with respiratory or cardiovascular symptoms. The emergency clinician must balance the benefit of reassuring negative PE testing with the risks of iatrogenic harms from over investigation and overdiagnosis.

AB - This first of two practice reviews addresses pulmonary embolism (PE) diagnosis considering important aspects of PE clinical presentation and comparing evidence-based PE testing strategies. A companion paper addresses the management of PE. Symptoms and signs of PE are varied, and emergency physicians frequently use testing to 'rule out' the diagnosis in people with respiratory or cardiovascular symptoms. The emergency clinician must balance the benefit of reassuring negative PE testing with the risks of iatrogenic harms from over investigation and overdiagnosis.

KW - diagnosis

KW - emergency care systems

KW - pulmonary embolism

KW - thrombo-embolic disease

U2 - 10.1136/emermed-2021-212000

DO - 10.1136/emermed-2021-212000

M3 - Article

C2 - 35868848

SN - 1472-0205

VL - 39

SP - 945

EP - 951

JO - Emergency Medicine Journal

JF - Emergency Medicine Journal

IS - 12

M1 - emermed-2021-212000

ER -

Pulmonary embolism diagnosis: clinical assessment at the front door

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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