Pulsatility in Neuroendocrine Systems

Gareth Leng, Nancy Sabatier, Celine Caquineau

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Abstract

Most hormones of the pituitary gland are secreted in a pulsatile manner when they are needed. The pulsatile pattern of secretion reflects (1) mechanisms to avoid desensitization of the target tissues in the periphery, thus achieving a biologically effective signal with a minimal production of hormone, and (2) biological strategies that exploit the nonlinearity of stimulus-secretion coupling in endocrine or neuroendocrine cells, ensuring an efficient secretory response to a minimally suprathreshold stimulus.
Original languageEnglish
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier
Pages1225-1232
Number of pages8
ISBN (Print)978-0-08-045046-9
DOIs
Publication statusPublished - 2009

Keywords

  • Dendrites
  • Follicle-stimulating hormone
  • Gonadotrophs
  • Growth hormone
  • Hypothalamus
  • Luteinizing hormone
  • Luteinizing hormone-releasing hormone
  • Milk ejection
  • Neuronal burst activation
  • Oxytocin
  • Release-inhibiting factor
  • Releasing factor
  • Self-priming
  • Vasopressin

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