QD-filled micelles which combine SPECT and optical imaging with light-induced activation of a platinum(IV) prodrug for anticancer applications

Carmen R Maldonado, Nina Gómez-Blanco, Maite Jauregui-Osoro, Valerie G Brunton, Luis Yate, Juan C Mareque-Rivas

Research output: Contribution to journalArticlepeer-review

Abstract

The fac-[(99m)Tc(OH2)3(CO)3](+) complex reacts with QD-filled micelles to create a bimodal SPECT-optical imaging probe which upon visible light irradiation generates cisplatin from an inert Pt(iv) prodrug.
Original languageEnglish
Pages (from-to)3985-3987
Number of pages3
JournalChemical Communications
Volume49
Issue number38
DOIs
Publication statusPublished - 11 May 2013

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