Quality of life and mild cognitive impairment in early Parkinson's disease: does subtype matter?

Rachael A Lawson; Alison J Yarnall; Gordon W Duncan; Tien K Khoo; David P Breen; Roger A Barker; Daniel Collerton; John-Paul Taylor; David J Burn

doi:10.3233/JPD-140390

Quality of life and mild cognitive impairment in early Parkinson's disease: does subtype matter?

Rachael A Lawson, Alison J Yarnall, Gordon W Duncan, Tien K Khoo, David P Breen, Roger A Barker, Daniel Collerton, John-Paul Taylor, David J Burn

Research output: Contribution to journal › Article › peer-review

Abstract

We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p > 0.10), suggesting that the nature of cognitive impairment is less significant than its severity.

Original language	English
Pages (from-to)	331-6
Number of pages	6
Journal	Journal of Parkinson's disease
Volume	4
Issue number	3
DOIs	https://doi.org/10.3233/JPD-140390
Publication status	Published - 2014

Keywords / Materials (for Non-textual outputs)

Aged
Cohort Studies
Female
Humans
Male
Middle Aged
Mild Cognitive Impairment
Neuropsychological Tests
Parkinson Disease
Quality of Life

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title = "Quality of life and mild cognitive impairment in early Parkinson's disease: does subtype matter?",

abstract = "We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p > 0.10), suggesting that the nature of cognitive impairment is less significant than its severity.",

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T1 - Quality of life and mild cognitive impairment in early Parkinson's disease

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AU - Lawson, Rachael A

AU - Yarnall, Alison J

AU - Duncan, Gordon W

AU - Khoo, Tien K

AU - Breen, David P

AU - Barker, Roger A

AU - Collerton, Daniel

AU - Taylor, John-Paul

AU - Burn, David J

PY - 2014

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N2 - We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p > 0.10), suggesting that the nature of cognitive impairment is less significant than its severity.

AB - We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p > 0.10), suggesting that the nature of cognitive impairment is less significant than its severity.

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KW - Middle Aged

KW - Mild Cognitive Impairment

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KW - Parkinson Disease

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Quality of life and mild cognitive impairment in early Parkinson's disease: does subtype matter?

Abstract

Keywords / Materials (for Non-textual outputs)

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