Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies

Isabel Fortier, Paul R. Burton, Paula J. Robson, Vincent Ferretti, Julian Little, Francois L'Heureux, Mylene Deschenes, Bartha M. Knoppers, Dany Doiron, Joost C. Keers, Pamela Linksted, Jennifer R. Harris, Genevieve Lachance, Catherine Boileau, Nancy L. Pedersen, Carol M. Hamilton, Kristian Hveem, Marilyn J. Borugian, Richard P. Gallagher, John McLaughlinLouise Parker, John D. Potter, John Gallacher, Rudolf Kaaks, Bette Liu, Tim Sprosen, Anne Vilain, Susan A. Atkinson, Andrea Rengifo, Robin Morton, Andres Metspalu, H. Erich Wichmann, Mark Tremblay, Rex L. Chisholm, Andres Garcia-Montero, Hans Hillege, Jan-Eric Litton, Lyle J. Palmer, Markus Perola, Bruce H. R. Wolffenbuttel, Leena Peltonen, Thomas J. Hudson

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Methods This conceptual article describes the origins, purpose and scientific foundations of the DataSHaPER (DataSchema and Harmonization Platform for Epidemiological Research; http://www.datashaper.org), which has been created by a multidisciplinary consortium of experts that was pulled together and coordinated by three international organizations: P(3)G (Public Population Project in Genomics), PHOEBE (Promoting Harmonization of Epidemiological Biobanks in Europe) and CPT (Canadian Partnership for Tomorrow Project).

Results The DataSHaPER provides a flexible, structured approach to the harmonization and pooling of information between studies. Its two primary components, the 'DataSchema' and 'Harmonization Platforms', together support the preparation of effective data-collection protocols and provide a central reference to facilitate harmonization. The DataSHaPER supports both 'prospective' and 'retrospective' harmonization.

Conclusion It is hoped that this article will encourage readers to investigate the project further: the more the research groups and studies are actively involved, the more effective the DataSHaPER programme will ultimately be.

Original languageEnglish
Pages (from-to)1383-1393
Number of pages11
JournalInternational Journal of Epidemiology
Issue number5
Publication statusPublished - Oct 2010


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