Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism

Mark Macaskill; Agne Stadulyte; Lewis Williams; Timaeus E. F. Morgan; Nikki L Sloan; Carlos Alcaide Corral; Tashfeen Walton; Catriona Wimberley; Chris-Anne McKenzie; Nick Spath; William Mungall; Ralph Bouhaidar; Marc R Dweck; Gillian Gray; David E Newby; Christophe Lucatelli; Andrew Sutherland; Sally Pimlott; Adriana A S Tavares

doi:10.2967/jnumed.120.243600

Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism

Mark Macaskill, Agne Stadulyte, Lewis Williams, Timaeus E. F. Morgan, Nikki L Sloan, Carlos Alcaide Corral, Tashfeen Walton, Catriona Wimberley, Chris-Anne McKenzie, Nick Spath, William Mungall, Ralph Bouhaidar, Marc R Dweck, Gillian Gray, David E Newby, Christophe Lucatelli, Andrew Sutherland, Sally Pimlott, Adriana A S Tavares

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Journal of Nuclear Medicine
Early online date	28 Aug 2020
DOIs	https://doi.org/10.2967/jnumed.120.243600
Publication status	E-pub ahead of print - 28 Aug 2020

Access to Document

10.2967/jnumed.120.243600Licence: Creative Commons: Attribution (CC-BY)

J Nucl Med-2020-MacAskill-jnumed.120.243600Final published version, 7.85 MBLicence: Creative Commons: Attribution (CC-BY)

Myocardial Fibrosis And Left Ventricular Remodelling In Cardiovascular Disease
Tavares, A. (Principal Investigator), Baker, A. (Co-investigator) & Newby, D. (Co-investigator)
UK-based charities
1/10/19 → 30/09/24
Project: Research
REA3 pump priming
Baker, A. (Principal Investigator)
UK-based charities
1/04/19 → 31/03/24
Project: Research
Novel imaging biomarker for detection of regional cardiovascular inflammation using Positron Emission Tomography (PET)
Tavares, A. (Principal Investigator)
UK-based charities
1/04/18 → 30/09/20
Project: Research

Quantification of Macrophage-Driven Inflammation During Myocardial Infarction with 18F-LW223, a Novel TSPO Radiotracer with Binding Independent of the rs6971 Human Polymorphism
Stadulyte, A. (Creator), Morgan, T. (Creator), Wimberley, C. (Creator), Alcaide Corral, C. (Creator), Tavares, A. A. S. (Creator) & Macaskill, M. (Creator), Edinburgh DataShare, 21 Jul 2022
DOI: 10.7488/ds/3489
Dataset

Edinburgh Preclinical Imaging
Moran, C. (Manager), Thomson, A. (Manager), Lennen, R. J. (Manager), Tavares, A. (Manager), Alcaide-Corral, C. J. (Manager), Morgan, T. (Other), Cranston, I. (Other) & O'Rourke, K. (Other)
Deanery of Clinical Sciences
Facility/equipment: Facility

Cite this

Macaskill, M., Stadulyte, A., Williams, L., Morgan, T. E. F., Sloan, N. L., Corral, C. A., Walton, T., Wimberley, C., McKenzie, C.-A., Spath, N., Mungall, W., Bouhaidar, R., Dweck, M. R., Gray, G., Newby, D. E., Lucatelli, C., Sutherland, A., Pimlott, S., & Tavares, A. A. S. (2020). Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism. Journal of Nuclear Medicine. Advance online publication. https://doi.org/10.2967/jnumed.120.243600

@article{ded6341e05794c9ebee1f2941854b116,

title = "Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism",

author = "Mark Macaskill and Agne Stadulyte and Lewis Williams and Morgan, {Timaeus E. F.} and Sloan, {Nikki L} and Corral, {Carlos Alcaide} and Tashfeen Walton and Catriona Wimberley and Chris-Anne McKenzie and Nick Spath and William Mungall and Ralph Bouhaidar and Dweck, {Marc R} and Gillian Gray and Newby, {David E} and Christophe Lucatelli and Andrew Sutherland and Sally Pimlott and Tavares, {Adriana A S}",

year = "2020",

month = aug,

day = "28",

doi = "10.2967/jnumed.120.243600",

language = "English",

journal = "Journal of Nuclear Medicine",

issn = "0161-5505",

publisher = "Society of Nuclear Medicine Inc.",

}

Macaskill, M, Stadulyte, A, Williams, L, Morgan, TEF, Sloan, NL, Corral, CA, Walton, T, Wimberley, C, McKenzie, C-A, Spath, N, Mungall, W, Bouhaidar, R, Dweck, MR, Gray, G, Newby, DE , Lucatelli, C, Sutherland, A, Pimlott, S & Tavares, AAS 2020, 'Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism', Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.120.243600

TY - JOUR

T1 - Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism

AU - Macaskill, Mark

AU - Stadulyte, Agne

AU - Williams, Lewis

AU - Morgan, Timaeus E. F.

AU - Sloan, Nikki L

AU - Corral, Carlos Alcaide

AU - Walton, Tashfeen

AU - Wimberley, Catriona

AU - McKenzie, Chris-Anne

AU - Spath, Nick

AU - Mungall, William

AU - Bouhaidar, Ralph

AU - Dweck, Marc R

AU - Gray, Gillian

AU - Newby, David E

AU - Lucatelli, Christophe

AU - Sutherland, Andrew

AU - Pimlott, Sally

AU - Tavares, Adriana A S

PY - 2020/8/28

Y1 - 2020/8/28

U2 - 10.2967/jnumed.120.243600

DO - 10.2967/jnumed.120.243600

M3 - Article

SN - 0161-5505

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

ER -

Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism

Access to Document

Projects

Myocardial Fibrosis And Left Ventricular Remodelling In Cardiovascular Disease

REA3 pump priming

Novel imaging biomarker for detection of regional cardiovascular inflammation using Positron Emission Tomography (PET)

Datasets

Quantification of Macrophage-Driven Inflammation During Myocardial Infarction with 18F-LW223, a Novel TSPO Radiotracer with Binding Independent of the rs6971 Human Polymorphism

Equipment

Edinburgh Preclinical Imaging

Cite this