Quantitation of alpha-1 proteinase-inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary-disease

Elspeth Milne; Alan Pemberton; Bruce McGorum; Padraic Dixon; C L  Scudamore; H R P  Miller

Quantitation of alpha-1 proteinase-inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary-disease

Elspeth Milne, Alan Pemberton, Bruce McGorum, Padraic Dixon, C L Scudamore, H R P Miller

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

The concentration of alpha-1 proteinase inhibitor (API) was measured in the pulmonary epithelial lining fluid (PELF) of horses with chronic obstructive pulmonary disease (COPD) while they had clinical signs and while they had none. The concentrations of total protein, albumin and API were significantly higher in the PELF of animals with clinical signs of COPD. The correlation between albumin and API in the PELF suggested that most of the API was derived from the serum.

Original language	English
Pages (from-to)	262-264
Number of pages	3
Journal	Research in Veterinary Science
Volume	57
Issue number	2
Publication status	Published - Sep 1994

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@article{478989814e694211929a0052375e1ad7,

title = "Quantitation of alpha-1 proteinase-inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary-disease",

abstract = "The concentration of alpha-1 proteinase inhibitor (API) was measured in the pulmonary epithelial lining fluid (PELF) of horses with chronic obstructive pulmonary disease (COPD) while they had clinical signs and while they had none. The concentrations of total protein, albumin and API were significantly higher in the PELF of animals with clinical signs of COPD. The correlation between albumin and API in the PELF suggested that most of the API was derived from the serum.",

author = "Elspeth Milne and Alan Pemberton and Bruce McGorum and Padraic Dixon and Scudamore, {C L} and Miller, {H R P}",

year = "1994",

month = sep,

language = "English",

volume = "57",

pages = "262--264",

journal = "Research in Veterinary Science",

issn = "0034-5288",

publisher = "ELSEVIER SCI LTD",

number = "2",

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TY - JOUR

T1 - Quantitation of alpha-1 proteinase-inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary-disease

AU - Milne, Elspeth

AU - Pemberton, Alan

AU - McGorum, Bruce

AU - Dixon, Padraic

AU - Scudamore, C L

AU - Miller, H R P

PY - 1994/9

Y1 - 1994/9

N2 - The concentration of alpha-1 proteinase inhibitor (API) was measured in the pulmonary epithelial lining fluid (PELF) of horses with chronic obstructive pulmonary disease (COPD) while they had clinical signs and while they had none. The concentrations of total protein, albumin and API were significantly higher in the PELF of animals with clinical signs of COPD. The correlation between albumin and API in the PELF suggested that most of the API was derived from the serum.

AB - The concentration of alpha-1 proteinase inhibitor (API) was measured in the pulmonary epithelial lining fluid (PELF) of horses with chronic obstructive pulmonary disease (COPD) while they had clinical signs and while they had none. The concentrations of total protein, albumin and API were significantly higher in the PELF of animals with clinical signs of COPD. The correlation between albumin and API in the PELF suggested that most of the API was derived from the serum.

M3 - Comment/debate

VL - 57

SP - 262

EP - 264

JO - Research in Veterinary Science

JF - Research in Veterinary Science

SN - 0034-5288

IS - 2

ER -

Quantitation of alpha-1 proteinase-inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary-disease

Abstract

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