Quantitation of alpha-1 proteinase-inhibitor in the pulmonary epithelial lining fluid of horses with chronic obstructive pulmonary-disease

Elspeth Milne, Alan Pemberton, Bruce McGorum, Padraic Dixon, C L Scudamore, H R P Miller

Research output: Contribution to journalComment/debatepeer-review

Abstract

The concentration of alpha-1 proteinase inhibitor (API) was measured in the pulmonary epithelial lining fluid (PELF) of horses with chronic obstructive pulmonary disease (COPD) while they had clinical signs and while they had none. The concentrations of total protein, albumin and API were significantly higher in the PELF of animals with clinical signs of COPD. The correlation between albumin and API in the PELF suggested that most of the API was derived from the serum.

Original languageEnglish
Pages (from-to)262-264
Number of pages3
JournalResearch in Veterinary Science
Volume57
Issue number2
Publication statusPublished - Sep 1994

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