Quantitative detection of seizures with minimal-density EEG montage using phase synchrony and cross-channel coherence amplitude in critical care

Shima Abdullateef*, Brian Jordan, Valerie Rae, Ailsa McLellan, Javier Escudero, Vera Nenadovic, Milly Lo

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Seizures frequently occur in paediatric emergency and critical care, with up to 74% being sub-clinical seizures making detection difficult. Delays in seizure detection and treatment worsen the neurological outcome of critically-ill patients. Gold-standard seizure detections using multi-channels electroencephalograms (EEG) require trained clinical physiologists to apply scalp electrodes and highly specialised neurologists to interpret and identify seizures. In this study, we extracted phase synchrony and cross-channel coherence amplitude across 4 and 8 pre-selected scalp EEG signals. Binary classification is used to determine whether the signal segment is seizure or non-seizure, and the predictions were compared against the gold-standard seizure onset markings. The application of the algorithm on a cohort of forty routinely collected EEGs from paediatric patients showed an average accuracy of 77.2 % and 76.5% using 4 and 8 channels, respectively. Clinical Relevance- This work demonstrates the feasibility of seizure detection with pre-defined 4 and 8 EEG electrodes with an average accuracy of 77%. This means for the first time seizure detection is possible using an EEG montage that can be applied readily at the bedside independent of expert input.

Original languageEnglish
Title of host publicationProceedings of the 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
PublisherIEEE Xplore
Pages259-262
Number of pages4
Volume2022
DOIs
Publication statusE-pub ahead of print - 8 Sep 2022
Event44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Glasgow, United Kingdom
Duration: 11 Jul 202215 Jul 2022
Conference number: 44
https://embc.embs.org/2022/

Conference

Conference44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Abbreviated titleEMBC 2022
Country/TerritoryUnited Kingdom
CityGlasgow
Period11/07/2215/07/22
Internet address

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