Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI

Yu-Yuan Xu; Francesca M. Chappell; Maria Valdes Hernandez; Carmen Arteaga Reyes; Una Clancy; Daniela Jaime Garcia; Stephen Makin; Michael Stringer; Michael Thrippleton; Stewart Wiseman; Yajun Cheng; Dillys Xiaodi Liu; Rosalind Brown; Fergus Doubal; Ian J. Deary; Simon Cox; Danielle Kerkhofs; Julie Staals; Walter Backes; Robert van Oostenbrugge; Anna Kopczak; Marco Duering; Joanna Wardlaw

doi:10.1161/STROKEAHA.125.055101

Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI

Yu-Yuan Xu
, Francesca M. Chappell
, Maria Valdes Hernandez
, Carmen Arteaga Reyes
, Una Clancy
, Daniela Jaime Garcia
, Stephen Makin
, Michael Stringer
, Michael Thrippleton
, Stewart Wiseman
, Yajun Cheng
, Dillys Xiaodi Liu
, Rosalind Brown
, Fergus Doubal
, Ian J. Deary
, Simon Cox
, Danielle Kerkhofs
, Julie Staals
, Walter Backes
, Robert van Oostenbrugge

Anna Kopczak, Marco Duering, Joanna Wardlaw^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Stroke
Early online date	15 Jul 2026
DOIs	https://doi.org/10.1161/STROKEAHA.125.055101
Publication status	E-pub ahead of print - 15 Jul 2026

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10.1161/STROKEAHA.125.055101

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Cite this

Xu, Y.-Y., Chappell, F. M., Valdes Hernandez, M., Arteaga Reyes, C., Clancy, U., Jaime Garcia, D., Makin, S., Stringer, M., Thrippleton, M., Wiseman, S., Cheng, Y., Liu, D. X., Brown, R., Doubal, F., Deary, I. J., Cox, S., Kerkhofs, D., Staals, J., Backes, W., ... Wardlaw, J. (2026). Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI. Stroke. Advance online publication. https://doi.org/10.1161/STROKEAHA.125.055101

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title = "Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI",

author = "Yu-Yuan Xu and Chappell, \{Francesca M.\} and \{Valdes Hernandez\}, Maria and \{Arteaga Reyes\}, Carmen and Una Clancy and \{Jaime Garcia\}, Daniela and Stephen Makin and Michael Stringer and Michael Thrippleton and Stewart Wiseman and Yajun Cheng and Liu, \{Dillys Xiaodi\} and Rosalind Brown and Fergus Doubal and Deary, \{Ian J.\} and Simon Cox and Danielle Kerkhofs and Julie Staals and Walter Backes and \{van Oostenbrugge\}, Robert and Anna Kopczak and Marco Duering and Joanna Wardlaw",

year = "2026",

month = jul,

day = "15",

doi = "10.1161/STROKEAHA.125.055101",

language = "English",

journal = "Stroke",

issn = "0039-2499",

publisher = "Wolters Kluwer Health",

}

Xu, Y-Y, Chappell, FM , Valdes Hernandez, M, Arteaga Reyes, C, Clancy, U , Jaime Garcia, D, Makin, S, Stringer, M , Thrippleton, M, Wiseman, S, Cheng, Y, Liu, DX, Brown, R , Doubal, F , Deary, IJ , Cox, S, Kerkhofs, D, Staals, J, Backes, W, van Oostenbrugge, R, Kopczak, A, Duering, M & Wardlaw, J 2026, 'Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI', Stroke. https://doi.org/10.1161/STROKEAHA.125.055101

TY - JOUR

T1 - Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI

AU - Xu, Yu-Yuan

AU - Chappell, Francesca M.

AU - Valdes Hernandez, Maria

AU - Arteaga Reyes, Carmen

AU - Clancy, Una

AU - Jaime Garcia, Daniela

AU - Makin, Stephen

AU - Stringer, Michael

AU - Thrippleton, Michael

AU - Wiseman, Stewart

AU - Cheng, Yajun

AU - Liu, Dillys Xiaodi

AU - Brown, Rosalind

AU - Doubal, Fergus

AU - Deary, Ian J.

AU - Cox, Simon

AU - Kerkhofs, Danielle

AU - Staals, Julie

AU - Backes, Walter

AU - van Oostenbrugge, Robert

AU - Kopczak, Anna

AU - Duering, Marco

AU - Wardlaw, Joanna

PY - 2026/7/15

Y1 - 2026/7/15

U2 - 10.1161/STROKEAHA.125.055101

DO - 10.1161/STROKEAHA.125.055101

M3 - Article

SN - 0039-2499

JO - Stroke

JF - Stroke

ER -