RADSeq: next-generation population genetics

John L Davey; Mark W Blaxter

doi:10.1093/bfgp/elq031

RADSeq: next-generation population genetics

John L Davey, Mark W Blaxter

Research output: Contribution to journal › Article › peer-review

Abstract

Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations. However, genome-scale population genetic studies have been accessible only to well-funded model systems. Restriction-site associated DNA sequencing, a method that samples at reduced complexity across target genomes, promises to deliver high resolution population genomic data-thousands of sequenced markers across many individuals-for any organism at reasonable costs. It has found application in wild populations and non-traditional study species, and promises to become an important technology for ecological population genomics.

Original language	English
Pages (from-to)	416-23
Number of pages	8
Journal	Briefings in functional genomics
Volume	9
Issue number	5-6
DOIs	https://doi.org/10.1093/bfgp/elq031
Publication status	Published - Dec 2010

Keywords / Materials (for Non-textual outputs)

Animals
Base Sequence
Genetic Variation
Genetics, Population
Genome
Humans
Phylogeny
Polymorphism, Single Nucleotide
Restriction Mapping
Sequence Analysis, DNA

Access to Document

10.1093/bfgp/elq031

RADSeq: next-generation population genetics
Freely available in PMC.
Final published version, 432 KB

Unwinding snail chirality by a massvie subtactive linkage analysis (MSLA)
Blaxter, M. (Principal Investigator)
BBSRC
10/11/08 → 9/11/11
Project: Research

Cite this

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title = "RADSeq: next-generation population genetics",

abstract = "Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations. However, genome-scale population genetic studies have been accessible only to well-funded model systems. Restriction-site associated DNA sequencing, a method that samples at reduced complexity across target genomes, promises to deliver high resolution population genomic data-thousands of sequenced markers across many individuals-for any organism at reasonable costs. It has found application in wild populations and non-traditional study species, and promises to become an important technology for ecological population genomics.",

keywords = "Animals, Base Sequence, Genetic Variation, Genetics, Population, Genome, Humans, Phylogeny, Polymorphism, Single Nucleotide, Restriction Mapping, Sequence Analysis, DNA",

author = "Davey, {John L} and Blaxter, {Mark W}",

year = "2010",

month = dec,

doi = "10.1093/bfgp/elq031",

language = "English",

volume = "9",

pages = "416--23",

journal = "Briefings in functional genomics",

issn = "2041-2657",

publisher = "Oxford University Press",

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T1 - RADSeq: next-generation population genetics

AU - Davey, John L

AU - Blaxter, Mark W

PY - 2010/12

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AB - Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations. However, genome-scale population genetic studies have been accessible only to well-funded model systems. Restriction-site associated DNA sequencing, a method that samples at reduced complexity across target genomes, promises to deliver high resolution population genomic data-thousands of sequenced markers across many individuals-for any organism at reasonable costs. It has found application in wild populations and non-traditional study species, and promises to become an important technology for ecological population genomics.

KW - Animals

KW - Base Sequence

KW - Genetic Variation

KW - Genetics, Population

KW - Genome

KW - Humans

KW - Phylogeny

KW - Polymorphism, Single Nucleotide

KW - Restriction Mapping

KW - Sequence Analysis, DNA

U2 - 10.1093/bfgp/elq031

DO - 10.1093/bfgp/elq031

M3 - Article

C2 - 21266344

SN - 2041-2657

VL - 9

SP - 416

EP - 423

JO - Briefings in functional genomics

JF - Briefings in functional genomics

IS - 5-6

ER -

RADSeq: next-generation population genetics

Abstract

Keywords / Materials (for Non-textual outputs)

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Projects

Unwinding snail chirality by a massvie subtactive linkage analysis (MSLA)

Cite this