Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies

G F Winter; J M Inglis; H A Cubie

Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies

G F Winter, J M Inglis, H A Cubie

College of Medicine and Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.

Original language	English
Pages (from-to)	329-30
Number of pages	2
Journal	Journal of Virological Methods
Volume	15
Issue number	4
Publication status	Published - Mar 1987

Keywords / Materials (for Non-textual outputs)

Antibodies, Monoclonal
Antibodies, Viral
Cells, Cultured
Centrifugation
Culture Techniques
Herpes Simplex
Humans
Simplexvirus
Time Factors

Cite this

@article{91fdf1e7a69b42f4a3dc210f25eb36fe,

title = "Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies",

abstract = "One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.",

keywords = "Antibodies, Monoclonal, Antibodies, Viral, Cells, Cultured, Centrifugation, Culture Techniques, Herpes Simplex, Humans, Simplexvirus, Time Factors",

author = "Winter, {G F} and Inglis, {J M} and Cubie, {H A}",

year = "1987",

month = mar,

language = "English",

volume = "15",

pages = "329--30",

journal = "Journal of Virological Methods",

issn = "0166-0934",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies

AU - Winter, G F

AU - Inglis, J M

AU - Cubie, H A

PY - 1987/3

Y1 - 1987/3

N2 - One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.

AB - One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.

KW - Antibodies, Monoclonal

KW - Antibodies, Viral

KW - Cells, Cultured

KW - Centrifugation

KW - Culture Techniques

KW - Herpes Simplex

KW - Humans

KW - Simplexvirus

KW - Time Factors

M3 - Article

C2 - 3034946

SN - 0166-0934

VL - 15

SP - 329

EP - 330

JO - Journal of Virological Methods

JF - Journal of Virological Methods

IS - 4

ER -

Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

Fingerprint

Cite this