Rapid diagnosis of herpes simplex virus infections in conventional and shell vial cell cultures using monoclonal antibodies

G F Winter, J M Inglis, H A Cubie

Research output: Contribution to journalArticlepeer-review

Abstract

One hundred specimens for herpes simplex virus (HSV) isolation were tested in parallel by conventional and by centrifugation-enhanced cell culture, followed by identification using monoclonal antibodies to HSV-1 and HSV-2. Sensitivity was comparable by the two methods; conventional culture was only marginally slower and was easier to fit into the routine of a busy laboratory. It is, therefore, advocated for HSV detection in clinical specimens.
Original languageEnglish
Pages (from-to)329-30
Number of pages2
JournalJournal of Virological Methods
Volume15
Issue number4
Publication statusPublished - Mar 1987

Keywords

  • Antibodies, Monoclonal
  • Antibodies, Viral
  • Cells, Cultured
  • Centrifugation
  • Culture Techniques
  • Herpes Simplex
  • Humans
  • Simplexvirus
  • Time Factors

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