Novel p-iodobenzoate-based labelling reagents are shown to be effective photocaged precursors for synthesizing biomolecular radicals site-selectively in the gaseous and condensed phases. In vacuo, a single pulse of UV photons (266 nm) is sufficient to quantitatively photolyse the C-I bond. In aqueous solutions, the photolysis half-life is estimated to be 2.5 minutes when irradiating with a 15 W compact fluorescent lamp (254 nm).
|Number of pages||3|
|Early online date||24 Jan 2011|
|Publication status||Published - 14 Mar 2011|
- DIRECTED DISSOCIATION
- RIBONUCLEOTIDE REDUCTASE