Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Wellcome Trust Case Control Consortium; Detelina Grozeva; George Kirov; Dobril Ivanov; Ian R Jones; Lisa Jones; Elaine K Green; David M St Clair; Allan H Young; Nicol Ferrier; Anne E Farmer; Peter McGuffin; Peter A Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock

doi:10.1001/archgenpsychiatry.2010.25

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Wellcome Trust Case Control Consortium
, Detelina Grozeva
, George Kirov
, Dobril Ivanov
, Ian R Jones
, Lisa Jones
, Elaine K Green
, David M St Clair
, Allan H Young
, Nicol Ferrier
, Anne E Farmer
, Peter McGuffin
, Peter A Holmans
, Michael J Owen
, Michael C O'Donovan
, Nick Craddock

College of Medicine and Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including neuropsychiatric disorders such as schizophrenia and autism. The possible involvement of copy number variants (CNVs) in bipolar disorder has received little attention to date.

Original language	English
Pages (from-to)	318-27
Number of pages	10
Journal	Archives of General Psychiatry
Volume	67
Issue number	4
DOIs	https://doi.org/10.1001/archgenpsychiatry.2010.25
Publication status	Published - 2010

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Wellcome Trust Case Control Consortium, Grozeva, D., Kirov, G., Ivanov, D., Jones, I. R., Jones, L., Green, E. K., St Clair, D. M., Young, A. H., Ferrier, N., Farmer, A. E., McGuffin, P., Holmans, P. A., Owen, M. J., O'Donovan, M. C., & Craddock, N. (2010). Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia. Archives of General Psychiatry, 67(4), 318-27. https://doi.org/10.1001/archgenpsychiatry.2010.25

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author = "\{Wellcome Trust Case Control Consortium\} and Detelina Grozeva and George Kirov and Dobril Ivanov and Jones, \{Ian R\} and Lisa Jones and Green, \{Elaine K\} and \{St Clair\}, \{David M\} and Young, \{Allan H\} and Nicol Ferrier and Farmer, \{Anne E\} and Peter McGuffin and Holmans, \{Peter A\} and Owen, \{Michael J\} and O'Donovan, \{Michael C\} and Nick Craddock",

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doi = "10.1001/archgenpsychiatry.2010.25",

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Wellcome Trust Case Control Consortium, Grozeva, D, Kirov, G, Ivanov, D, Jones, IR, Jones, L, Green, EK, St Clair, DM, Young, AH, Ferrier, N, Farmer, AE, McGuffin, P, Holmans, PA, Owen, MJ, O'Donovan, MC & Craddock, N 2010, 'Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia', Archives of General Psychiatry, vol. 67, no. 4, pp. 318-27. https://doi.org/10.1001/archgenpsychiatry.2010.25

TY - JOUR

T1 - Rare copy number variants

T2 - a point of rarity in genetic risk for bipolar disorder and schizophrenia

AU - Wellcome Trust Case Control Consortium

AU - Grozeva, Detelina

AU - Kirov, George

AU - Ivanov, Dobril

AU - Jones, Ian R

AU - Jones, Lisa

AU - Green, Elaine K

AU - St Clair, David M

AU - Young, Allan H

AU - Ferrier, Nicol

AU - Farmer, Anne E

AU - McGuffin, Peter

AU - Holmans, Peter A

AU - Owen, Michael J

AU - O'Donovan, Michael C

AU - Craddock, Nick

PY - 2010

Y1 - 2010

N2 - Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including neuropsychiatric disorders such as schizophrenia and autism. The possible involvement of copy number variants (CNVs) in bipolar disorder has received little attention to date.

AB - Recent studies suggest that copy number variation in the human genome is extensive and may play an important role in susceptibility to disease, including neuropsychiatric disorders such as schizophrenia and autism. The possible involvement of copy number variants (CNVs) in bipolar disorder has received little attention to date.

U2 - 10.1001/archgenpsychiatry.2010.25

DO - 10.1001/archgenpsychiatry.2010.25

M3 - Article

C2 - 20368508

VL - 67

SP - 318

EP - 327

JO - Archives of General Psychiatry

JF - Archives of General Psychiatry

IS - 4

ER -

Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia

Abstract

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