Recent advances in the field of Salmonella Typhi vaccines.

Gavin Paterson, Duncan J Maskell

Research output: Contribution to journalArticlepeer-review

Abstract

Typhoid fever, caused by the bacterium Salmonella enterica serovar Typhi, remains a significant cause of human death and disease throughout large areas of the world. Although there are currently three vaccines available against S. Typhi they have a number of significant drawbacks which drive the development of much-needed new and improved versions. Here recent advances towards such vaccines, from basic research to human trials, are discussed.
Original languageEnglish
Pages (from-to)379-84
JournalHuman vaccines
Volume6
Issue number5
DOIs
Publication statusE-pub ahead of print - 1 May 2010

Keywords

  • typhoid fever
  • Salmonella Typhi
  • vaccine
  • bacterial infection
  • Salmonella Typhimurium
  • live attenuated vaccine
  • Subunit vaccine
  • polysaccharide vaccine

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