Abstract / Description of output
Typhoid fever, caused by the bacterium Salmonella enterica serovar Typhi, remains a significant cause of human death and disease throughout large areas of the world. Although there are currently three vaccines available against S. Typhi they have a number of significant drawbacks which drive the development of much-needed new and improved versions. Here recent advances towards such vaccines, from basic research to human trials, are discussed.
Original language | English |
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Pages (from-to) | 379-84 |
Journal | Human vaccines |
Volume | 6 |
Issue number | 5 |
DOIs | |
Publication status | E-pub ahead of print - 1 May 2010 |
Keywords / Materials (for Non-textual outputs)
- typhoid fever
- Salmonella Typhi
- vaccine
- bacterial infection
- Salmonella Typhimurium
- live attenuated vaccine
- Subunit vaccine
- polysaccharide vaccine