RECURRENCE OF COLORECTAL-CANCER AFTER SUTURED AND STAPLED LARGE-BOWEL ANASTOMOSES

AM AKYOL*, Peter Gregor MCGREGOR, DJ GALLOWAY, G MURRAY, WD GEORGE

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this study was to compare surgical stapling and manual suturing techniques with respect to the incidence of tumour recurrence in patients with colorectal cancer: 294 patients undergoing potentially curative resections for colorectal cancer were randomly allocated to receive sutured (n = 142) or stapled (n = 152) anastomoses. The mean(s.e.m.) incidence of tumour recurrence at the end of 24 months was 29.4(4.4) per cent in the sutured group, compared with 19.1(3.9) per cent in the stapled group (P <0.05). The corresponding rates for cancer-specific mortality at 24 months were 22.3(4.1) per cent and 10.9(3.0) per cent respectively (P <0.01). A multiple regression analysis revealed that the influence of anastomotic technique on recurrence and mortality rate was independent of tumour stage. These results suggest that in colorectal cancer surgery the use of stapling instruments for anastomotic construction could be associated with a reduction in the incidence of recurrence and mortality rate by as much as 50 per cent.

Original languageEnglish
Pages (from-to)1297-1300
Number of pages4
JournalBritish Journal of Surgery
Volume78
Issue number11
Publication statusPublished - Nov 1991

Keywords

  • LOW ANTERIOR RESECTION
  • EEA STAPLER
  • IMPLANTATION METASTASIS
  • LOCAL RECURRENCE
  • RECTAL-CARCINOMA
  • GUN
  • PRESERVATION
  • EXPERIENCE
  • SPHINCTER

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