Red blood cell distribution width as a prognostic factor in critically ill dogs: (December 2016 to April 2017): 127 cas

Marta Garcia Arce, Adam Gow, Ian Handel, W. Ngoi, Emily Thomas

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the association between red blood cell distribution width (RDW) and in-hospital mortality, length of hospitalization and leukocyte count in critically ill dogs.
Design: Retrospective study.
Setting: University teaching hospital.
Animals: One hundred and twenty-seven dogs admitted to the ICU from December 2016 to April 2017. Patients were included if they had a CBC performed within the first 24 hours of admission.
Interventions: None.
Measurements and Main Results: The overall in-hospital mortality rate was 29% (37/127) and median length of hospital stay was 3 days (IQR 1-6). The median RDW value was 13.8% (IQR 13.1-14.7%; reference range 11.9-14.5 %). The canine acute patient physiologic and laboratory evaluation (APPLE) fast score was calculated in 81/127 (64%) patients, the median score was 24/50 (IQR 20-29). There was no significant correlation between RDW and APPLE fast score (P = 0.163). Sub-group analysis was performed according to the following diagnostic categories: abdominal (36%; 46/127), hematological (13%; 16/127), respiratory (13%; 16/127), neurological (12%; 15/127), cardiovascular (11%; 14/127), integument (3%; 4/127), trauma (3%; 4/127), musculoskeletal (2%; 3/127) and other (7%; 9/127). Elevated RDW was not associated with in-hospital mortality overall (P = 0.381) nor in any individual sub-group analysis. No association was found between length of hospitalization and RDW values in either survivors (P = 0.548) or non-survivors (P = 0.083). The correlation between RDW and leukocyte count was non significant (P = 0.12).

Conclusions: In this study admission RDW was not associated with in-hospital mortality or length of hospitalization in critically ill dogs. The correlation between RDW and leukocyte count was non significant.
Original languageEnglish
JournalJournal of Veterinary Emergency and Critical Care
Early online date21 Dec 2021
DOIs
Publication statusE-pub ahead of print - 21 Dec 2021

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