Projects per year
Activation of plant immunity is associated with dramatic changes in the cellular redox status. Both oxidative and reductive bursts have been described that trigger a set of down stream responses resulting in reprogramming of the transcriptome and establishment of disease resistance. Nonetheless, how these redox changes are sensed and signal to downstream regulators remained a missing link in studies of plant immunity. Emerging evidence now indicates that pathogen-induced changes in the cellular redox environment are sensed by reactive cysteine residues of key regulatory proteins. Varying degrees of reversible, oxidative cysteine modifications control the activity, localization, protein-interaction and stability of regulatory proteins. These diverse effects on protein function make post-translational redox-based modifications potent modulators of plant immunity.
- 2 Finished
1/10/10 → 30/09/15
1/09/09 → 28/02/13
Spoel, S., 2013.
Research output: Contribution to conference › Abstract
Spoel, S. H. & Loake, G. J., Aug 2012, In: Current opinion in plant biology.
Research output: Contribution to journal › Literature review › peer-review