Regional Heritability Mapping of Production Traits in Epidemic Porcine Reproductive and Respiratory Syndrome

Christopher, M. Orrett, N. Deeb, Ricardo Pong-Wong, Oswald Matika, C. R. G. Lewis, D. G. McLaren, Alan Archibald, Stephen Bishop

Research output: Contribution to conferencePaper

Abstract

Porcine Reproductive and Respiratory Syndrome (PRRS) is an important disease of pigs. Sow farrowing and service data were obtained from two commercial pig multiplication units which experienced several confirmed PRRS outbreaks. Genomic regions associated with reproductive failure during PRRS outbreaks were investigated using a regional heritability mapping (RHM) approach combining the two datasets. Covariates were explored both fitting and ignoring the shape of the epidemic. Heritability (h2) of farrowing mortality (FMOR, proportion of dead piglets per litter) was 0.084 ignoring the epidemic shape and 0.059 fitting it. The additive genetic variance was non-estimable for the FMOR trait during non-epidemic phase. Two regions were significantly associated with FMOR at the genome-wide level, on Sus scrofa chromosomes (SSCs) 4 and 7, with several other regions approaching significance. A single SNP on SSC4 was significantly associated (P<0.001) with FMOR.
Original languageEnglish
Pages100
Publication statusPublished - 2014
EventProceedings, 10 th World Congress of Genetics Applied to Livestock Production - Canada, Vancouver, Canada
Duration: 17 Aug 201422 Aug 2014

Conference

ConferenceProceedings, 10 th World Congress of Genetics Applied to Livestock Production
Country/TerritoryCanada
CityVancouver
Period17/08/1422/08/14

Keywords

  • Pig
  • PRRS
  • Regional Heritability Mapping

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