Regulating the regulator: Nitric oxide control of post‐translational modifications

Jagadis Gupta Kapuganti; Zsuzsanna. Kolbert; Jorg Durner; Christian Lindermayr; Francisco J. Corpas; Renaud Brouquisse; Juan B. Barroso; Saima Umbreen; José M. Palma; John T. Hancock; Marek Petrivalsky; David Wendehenne; Gary J. Loake

doi:10.1111/nph.16622

Regulating the regulator: Nitric oxide control of post‐translational modifications

Jagadis Gupta Kapuganti, Zsuzsanna. Kolbert, Jorg Durner, Christian Lindermayr, Francisco J. Corpas, Renaud Brouquisse, Juan B. Barroso, Saima Umbreen, José M. Palma, John T. Hancock, Marek Petrivalsky, David Wendehenne, Gary J. Loake

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Nitric oxide (NO) is perfectly suited for duties as a redox signalling molecule. A key route for NO
bioactivity occurs via protein S-nitrosation, the addition of a NO moiety to a protein cysteine
(Cys) thiol (-SH) to form a S-nitrosothiol (SNO). This process is thought to underpin a myriad of
cellular processes in plants linked to development, environmental responses and immune function.
Here we collate emerging evidence showing that NO bioactivity regulates a growing number of
diverse post-translational modifications (PTMs) including SUMOylation, phosphorylation,
persulfidation and acetylation. We provide examples of how NO orchestrates these processes to
mediate plant adaptation to a variety of cellular cues.

Original language	English
Journal	New Phytologist
DOIs	https://doi.org/10.1111/nph.16622
Publication status	Published - 27 Apr 2020

Keywords / Materials (for Non-textual outputs)

nitric oxide
phosphorylation
s-nitrosation
SUMOylation
S-nitrosylation
persulfidation
reactive nitrogen species (RNS)
reactive oxygen species (ROS)

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10.1111/nph.16622

LoakeEtal2020RegulatingTheRegulatorNitricOxideControlOfPost
This is the peer reviewed version of the following article: 'Kapuganti, J.G., Kolbert, Z., Durner, J., Lindermayr, C., Corpas, F.J., Brouquisse, R., Barroso, J.B., Umbreen, S., Palma, J.M., Hancock, J.T., Petrivalsky, M., Wendehenne, D. and Loake, G.J. (2020), Regulating the regulator: nitric oxide control of post‐translational modifications. New Phytol. Accepted Author Manuscript. doi:10.1111/nph.16622 which has been published in final form at https://doi.org/10.1111/nph.16622 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."
Accepted author manuscript, 851 KB

Cite this

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title = "Regulating the regulator: Nitric oxide control of post‐translational modifications",

abstract = "Nitric oxide (NO) is perfectly suited for duties as a redox signalling molecule. A key route for NObioactivity occurs via protein S-nitrosation, the addition of a NO moiety to a protein cysteine(Cys) thiol (-SH) to form a S-nitrosothiol (SNO). This process is thought to underpin a myriad ofcellular processes in plants linked to development, environmental responses and immune function.Here we collate emerging evidence showing that NO bioactivity regulates a growing number ofdiverse post-translational modifications (PTMs) including SUMOylation, phosphorylation,persulfidation and acetylation. We provide examples of how NO orchestrates these processes tomediate plant adaptation to a variety of cellular cues. ",

keywords = "nitric oxide, phosphorylation, s-nitrosation, SUMOylation, S-nitrosylation, persulfidation, reactive nitrogen species (RNS), reactive oxygen species (ROS)",

author = "Kapuganti, {Jagadis Gupta} and Zsuzsanna. Kolbert and Jorg Durner and Christian Lindermayr and Corpas, {Francisco J.} and Renaud Brouquisse and Barroso, {Juan B.} and Saima Umbreen and Palma, {Jos{\'e} M.} and Hancock, {John T.} and Marek Petrivalsky and David Wendehenne and Loake, {Gary J.}",

year = "2020",

month = apr,

day = "27",

doi = "10.1111/nph.16622",

language = "English",

journal = "New Phytologist",

issn = "0028-646X",

publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Regulating the regulator

T2 - Nitric oxide control of post‐translational modifications

AU - Kapuganti, Jagadis Gupta

AU - Kolbert, Zsuzsanna.

AU - Durner, Jorg

AU - Lindermayr, Christian

AU - Corpas, Francisco J.

AU - Brouquisse, Renaud

AU - Barroso, Juan B.

AU - Umbreen, Saima

AU - Palma, José M.

AU - Hancock, John T.

AU - Petrivalsky, Marek

AU - Wendehenne, David

AU - Loake, Gary J.

PY - 2020/4/27

Y1 - 2020/4/27

N2 - Nitric oxide (NO) is perfectly suited for duties as a redox signalling molecule. A key route for NObioactivity occurs via protein S-nitrosation, the addition of a NO moiety to a protein cysteine(Cys) thiol (-SH) to form a S-nitrosothiol (SNO). This process is thought to underpin a myriad ofcellular processes in plants linked to development, environmental responses and immune function.Here we collate emerging evidence showing that NO bioactivity regulates a growing number ofdiverse post-translational modifications (PTMs) including SUMOylation, phosphorylation,persulfidation and acetylation. We provide examples of how NO orchestrates these processes tomediate plant adaptation to a variety of cellular cues.

AB - Nitric oxide (NO) is perfectly suited for duties as a redox signalling molecule. A key route for NObioactivity occurs via protein S-nitrosation, the addition of a NO moiety to a protein cysteine(Cys) thiol (-SH) to form a S-nitrosothiol (SNO). This process is thought to underpin a myriad ofcellular processes in plants linked to development, environmental responses and immune function.Here we collate emerging evidence showing that NO bioactivity regulates a growing number ofdiverse post-translational modifications (PTMs) including SUMOylation, phosphorylation,persulfidation and acetylation. We provide examples of how NO orchestrates these processes tomediate plant adaptation to a variety of cellular cues.

KW - nitric oxide

KW - phosphorylation

KW - s-nitrosation

KW - SUMOylation

KW - S-nitrosylation

KW - persulfidation

KW - reactive nitrogen species (RNS)

KW - reactive oxygen species (ROS)

U2 - 10.1111/nph.16622

DO - 10.1111/nph.16622

M3 - Article

SN - 0028-646X

JO - New Phytologist

JF - New Phytologist

ER -

Regulating the regulator: Nitric oxide control of post‐translational modifications

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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Cite this