Regulation and feedback of cholesterol metabolism

Alexander Mazein, Steven Watterson, Holly Gibbs, Wayne Hsieh, Mohammed Ba Abdullah, Mathieu Blanc, William J Griffths, Tom Freeman, Peter Ghazal

Research output: Working paper

Abstract / Description of output

Cholesterol biosynthesis serves as a central metabolic hub for numerous biological processes in health and disease. An integrative knowledge representation of how the cholesterol pathway is structured and how it interacts with other pathway systems is lacking. Here we provide using Systems Biology Graphical Notation the research synthesis of a process diagram integrating the regulatory and feedback systems for cholesterol synthesis.
Original languageEnglish
PublisherNature Publishing Group
DOIs
Publication statusPublished - 2011

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