Regulation of proliferation of bone marrow-derived macrophages

D A Hume, W Allan, B Fabrus, M J Weidemann, A J Hapel, S Bartelmez

Research output: Contribution to journalArticlepeer-review

Abstract

The rate of mobilisation of macrophages from marrow is an important determinant of the outcome of many pathological lesions. Studies of BMDM have provided insight into the complex feedback regulation that may control macrophage production. In addition BMDM possess several properties in common with transformed cells of other tissue origins and an understanding of their growth regulation may provide an insight into the mechanism of malignant transformation.
Original languageEnglish
Pages (from-to)127-39
Number of pages13
JournalLymphokine research
Volume6
Issue number2
Publication statusPublished - 1987

Keywords

  • Animals
  • Bone Marrow
  • Bone Marrow Cells
  • Cell Division
  • Colony-Stimulating Factors
  • Growth Inhibitors
  • Hematopoiesis
  • Interleukin-3
  • Lipopolysaccharides
  • Macrophages
  • Mice
  • Receptors, Cell Surface
  • Receptors, Colony-Stimulating Factor
  • Tetradecanoylphorbol Acetate

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