Regulation of the RNAPII Pool Is Integral to the DNA Damage Response

Ana Tufegdžić Vidaković, Richard Mitter, Gavin P. Kelly, Michelle Neumann, Michelle Harreman, Marta Rodríguez-Martínez, Anna Herlihy, Juston C. Weems, Stefan Boeing, Vesela Encheva, Liam Gaul, Laura Milligan, David Tollervey, Ronald C. Conaway, Joan W. Conaway, Ambrosius P. Snijders, Aengus Stewart, Jesper Q. Svejstrup*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Control of the pool of available RNA polymerase II shapes how cells respond to UV stress and the efficacy of the resulting damage response.

Original languageEnglish
Pages (from-to)1245-1261.e21
JournalCell
Volume180
Issue number6
DOIs
Publication statusPublished - 5 Mar 2020

Keywords

  • DNA damage
  • RNA polymerase II
  • transcription
  • ubiquitin
  • ubiquitylation
  • UV irradiation

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