Relationship between vitamin D status and clinical outcomes in dogs with a cranial cruciate ligament rupture

Dylan Clements; John Ryan; Ian Handel; Adam Gow; Susan Campbell; Emma Hurst; Richard Mellanby

doi:10.1016/j.rvsc.2021.03.019

Relationship between vitamin D status and clinical outcomes in dogs with a cranial cruciate ligament rupture

Dylan Clements, John Ryan, Ian Handel, Adam Gow, Susan Campbell, Emma Hurst, Richard Mellanby

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Cranial cruciate ligament rupture (CCLR) is one of the most common orthopaedic disorders diagnosed in dogs yet the factors which influence postoperative clinical outcomes are poorly understood. Low vitamin D status has been linked to poorer clinical outcomes in human patients undergoing elective orthopaedic surgery. The aim of this study was to examine the relationship between pre-operative vitamin D status, as defined by serum 25 hydroxyvitamin D (25(OH)D) concentrations, and initial disease severity and clinical outcomes in dogs undergoing surgical treatment for a CCLR .

Original language	English
Journal	Research in Veterinary Science
Early online date	25 Mar 2021
DOIs	https://doi.org/10.1016/j.rvsc.2021.03.019
Publication status	E-pub ahead of print - 25 Mar 2021

Keywords / Materials (for Non-textual outputs)

cranial cruciate ligament rupture
dog
vitamin D
25 hydroxyvitamin D

Access to Document

10.1016/j.rvsc.2021.03.019

vitamin D cruciate outcomes 7-10-20 no track changesAccepted author manuscript, 600 KBLicence: Creative Commons: Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)

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title = "Relationship between vitamin D status and clinical outcomes in dogs with a cranial cruciate ligament rupture",

abstract = "Cranial cruciate ligament rupture (CCLR) is one of the most common orthopaedic disorders diagnosed in dogs yet the factors which influence postoperative clinical outcomes are poorly understood. Low vitamin D status has been linked to poorer clinical outcomes in human patients undergoing elective orthopaedic surgery. The aim of this study was to examine the relationship between pre-operative vitamin D status, as defined by serum 25 hydroxyvitamin D (25(OH)D) concentrations, and initial disease severity and clinical outcomes in dogs undergoing surgical treatment for a CCLR .",

keywords = "cranial cruciate ligament rupture, dog, vitamin D, 25 hydroxyvitamin D",

author = "Dylan Clements and John Ryan and Ian Handel and Adam Gow and Susan Campbell and Emma Hurst and Richard Mellanby",

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T1 - Relationship between vitamin D status and clinical outcomes in dogs with a cranial cruciate ligament rupture

AU - Clements, Dylan

AU - Ryan, John

AU - Handel, Ian

AU - Gow, Adam

AU - Campbell, Susan

AU - Hurst, Emma

AU - Mellanby, Richard

PY - 2021/3/25

Y1 - 2021/3/25

N2 - Cranial cruciate ligament rupture (CCLR) is one of the most common orthopaedic disorders diagnosed in dogs yet the factors which influence postoperative clinical outcomes are poorly understood. Low vitamin D status has been linked to poorer clinical outcomes in human patients undergoing elective orthopaedic surgery. The aim of this study was to examine the relationship between pre-operative vitamin D status, as defined by serum 25 hydroxyvitamin D (25(OH)D) concentrations, and initial disease severity and clinical outcomes in dogs undergoing surgical treatment for a CCLR .

AB - Cranial cruciate ligament rupture (CCLR) is one of the most common orthopaedic disorders diagnosed in dogs yet the factors which influence postoperative clinical outcomes are poorly understood. Low vitamin D status has been linked to poorer clinical outcomes in human patients undergoing elective orthopaedic surgery. The aim of this study was to examine the relationship between pre-operative vitamin D status, as defined by serum 25 hydroxyvitamin D (25(OH)D) concentrations, and initial disease severity and clinical outcomes in dogs undergoing surgical treatment for a CCLR .

KW - cranial cruciate ligament rupture

KW - dog

KW - vitamin D

KW - 25 hydroxyvitamin D

U2 - 10.1016/j.rvsc.2021.03.019

DO - 10.1016/j.rvsc.2021.03.019

M3 - Article

SN - 0034-5288

JO - Research in Veterinary Science

JF - Research in Veterinary Science

ER -

Relationship between vitamin D status and clinical outcomes in dogs with a cranial cruciate ligament rupture

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Keywords / Materials (for Non-textual outputs)

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