Abstract / Description of output
Thank you to Xue et al. for their review of our paper 1, highlighting common concerns regarding perioperative administration of intravenous contrast media.
Our study was one of the largest prospective, multicentre studies on acute kidney injury (AKI) in this population 2. We agree there are several additional datapoints which may have been of interest within the current analysis. However, the granularity of data collected was limited due to a pragmatic approach to study design within a student/trainee-led group; typically having to be limited to 10-15 pre-, intra- and postoperative unique datapoints. Given radiology guidelines generally advise to use the minimum effective dose of contrast media for imaging and no evidence that commonly used contrast media (iso- or low osmolarity) were significantly associated with AKI 2, it was felt that there was insufficient justification to prioritise collection.
Our study was one of the largest prospective, multicentre studies on acute kidney injury (AKI) in this population 2. We agree there are several additional datapoints which may have been of interest within the current analysis. However, the granularity of data collected was limited due to a pragmatic approach to study design within a student/trainee-led group; typically having to be limited to 10-15 pre-, intra- and postoperative unique datapoints. Given radiology guidelines generally advise to use the minimum effective dose of contrast media for imaging and no evidence that commonly used contrast media (iso- or low osmolarity) were significantly associated with AKI 2, it was felt that there was insufficient justification to prioritise collection.
Original language | English |
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Journal | BJS Open |
Publication status | Published - 31 Jul 2020 |