Response to comment on 10.1002/bjs.11453

Kenneth Mclean, Ahmed Wu, M Akhbari, D Nepogodiev

Research output: Contribution to journalLetter


Thank you to Xue et al. for their review of our paper 1, highlighting common concerns regarding perioperative administration of intravenous contrast media.
Our study was one of the largest prospective, multicentre studies on acute kidney injury (AKI) in this population 2. We agree there are several additional datapoints which may have been of interest within the current analysis. However, the granularity of data collected was limited due to a pragmatic approach to study design within a student/trainee-led group; typically having to be limited to 10-15 pre-, intra- and postoperative unique datapoints. Given radiology guidelines generally advise to use the minimum effective dose of contrast media for imaging and no evidence that commonly used contrast media (iso- or low osmolarity) were significantly associated with AKI 2, it was felt that there was insufficient justification to prioritise collection.
Original languageEnglish
JournalBJS Open
Publication statusPublished - 31 Jul 2020


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