Responsive poly (gamma-glutamic acid) fibres for biomedical applications

Sangwon Chung*, Cristina Gentilini, Anthony Callanan, Martin Hedegaard, Soren Hassing, Molly M. Stevens

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

A novel responsive system using a protein-based biopolymer was designed to undergo structural, geometric, and chemical changes upon temperature change or solvent interaction. Poly(g-glutamic acid) (gamma-PGA) is an attractive candidate for various biomedical applications as it is naturally produced, biocompatible and enzymatically degradable. The responsive material was fabricated using an electrospun modified gamma-PGA to create a sub-micron fibrous mat. By modulating the environment responsive behaviour in a controlled manner, exciting applications such as wound dressing, compression materials and self-tightening knots are envisaged.

Original languageEnglish
Pages (from-to)1397-1401
Number of pages5
JournalJournal of Materials Chemistry B: Materials for biology and medicine
Volume1
Issue number10
DOIs
Publication statusPublished - 2013

Keywords / Materials (for Non-textual outputs)

  • POLY(GAMMA-GLUTAMIC ACID)
  • NON-AQUEOUS SOLVENTS
  • HYDROGELS
  • THERMAL SHRINKAGE
  • TEXTILE FIBERS

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