RFLP and linkage analysis of the porcine casein loci--CASAS1, CASAS2, CASB and CASK

A L Archibald; S Couperwhite; C S Haley; C W Beattie; L J Alexander

RFLP and linkage analysis of the porcine casein loci--CASAS1, CASAS2, CASB and CASK

A L Archibald, S Couperwhite, C S Haley, C W Beattie, L J Alexander

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Restriction fragment length polymorphisms (RFLPs) were revealed at the porcine casein loci with the following combinations of restriction endonucleases and porcine cDNA clones: alpha s1-casein (TaqI); alpha s2-casein (BamHI); and beta-casein (SacI). These RFLPs were shown to be under simple monogenic control by segregation analysis of two- and three-generation families. The CASAS1, CASAS2 and CASB casein loci were also shown to be linked with no recombinant haplotypes observed amongst 77 meioses in Large White and Meishan F1 and F2 crosses. No recombinants were observed in a further 106 meioses that were informative for linkage between CASAS1 and CASAS2.

Original language	English
Pages (from-to)	349-51
Number of pages	3
Journal	Animal Genetics
Volume	25
Issue number	5
Publication status	Published - Oct 1994

Keywords / Materials (for Non-textual outputs)

Alleles
Animals
Caseins
Crosses, Genetic
Deoxyribonuclease BamHI
Deoxyribonucleases, Type II Site-Specific
Female
Genetic Linkage
Humans
Infant, Newborn
Male
Meiosis
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Recombination, Genetic
Restriction Mapping
Species Specificity
Swine

Cite this

@article{edeb86648438404a9915a25f2a0ea329,

title = "RFLP and linkage analysis of the porcine casein loci--CASAS1, CASAS2, CASB and CASK",

abstract = "Restriction fragment length polymorphisms (RFLPs) were revealed at the porcine casein loci with the following combinations of restriction endonucleases and porcine cDNA clones: alpha s1-casein (TaqI); alpha s2-casein (BamHI); and beta-casein (SacI). These RFLPs were shown to be under simple monogenic control by segregation analysis of two- and three-generation families. The CASAS1, CASAS2 and CASB casein loci were also shown to be linked with no recombinant haplotypes observed amongst 77 meioses in Large White and Meishan F1 and F2 crosses. No recombinants were observed in a further 106 meioses that were informative for linkage between CASAS1 and CASAS2.",

keywords = "Alleles, Animals, Caseins, Crosses, Genetic, Deoxyribonuclease BamHI, Deoxyribonucleases, Type II Site-Specific, Female, Genetic Linkage, Humans, Infant, Newborn, Male, Meiosis, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length, Recombination, Genetic, Restriction Mapping, Species Specificity, Swine",

author = "Archibald, {A L} and S Couperwhite and Haley, {C S} and Beattie, {C W} and Alexander, {L J}",

year = "1994",

month = oct,

language = "English",

volume = "25",

pages = "349--51",

journal = "Animal Genetics",

issn = "0268-9146",

publisher = "Wiley-Blackwell",

number = "5",

}

TY - JOUR

T1 - RFLP and linkage analysis of the porcine casein loci--CASAS1, CASAS2, CASB and CASK

AU - Archibald, A L

AU - Couperwhite, S

AU - Haley, C S

AU - Beattie, C W

AU - Alexander, L J

PY - 1994/10

Y1 - 1994/10

N2 - Restriction fragment length polymorphisms (RFLPs) were revealed at the porcine casein loci with the following combinations of restriction endonucleases and porcine cDNA clones: alpha s1-casein (TaqI); alpha s2-casein (BamHI); and beta-casein (SacI). These RFLPs were shown to be under simple monogenic control by segregation analysis of two- and three-generation families. The CASAS1, CASAS2 and CASB casein loci were also shown to be linked with no recombinant haplotypes observed amongst 77 meioses in Large White and Meishan F1 and F2 crosses. No recombinants were observed in a further 106 meioses that were informative for linkage between CASAS1 and CASAS2.

AB - Restriction fragment length polymorphisms (RFLPs) were revealed at the porcine casein loci with the following combinations of restriction endonucleases and porcine cDNA clones: alpha s1-casein (TaqI); alpha s2-casein (BamHI); and beta-casein (SacI). These RFLPs were shown to be under simple monogenic control by segregation analysis of two- and three-generation families. The CASAS1, CASAS2 and CASB casein loci were also shown to be linked with no recombinant haplotypes observed amongst 77 meioses in Large White and Meishan F1 and F2 crosses. No recombinants were observed in a further 106 meioses that were informative for linkage between CASAS1 and CASAS2.

KW - Alleles

KW - Animals

KW - Caseins

KW - Crosses, Genetic

KW - Deoxyribonuclease BamHI

KW - Deoxyribonucleases, Type II Site-Specific

KW - Female

KW - Genetic Linkage

KW - Humans

KW - Infant, Newborn

KW - Male

KW - Meiosis

KW - Polymorphism, Genetic

KW - Polymorphism, Restriction Fragment Length

KW - Recombination, Genetic

KW - Restriction Mapping

KW - Species Specificity

KW - Swine

M3 - Article

C2 - 7818172

SN - 0268-9146

VL - 25

SP - 349

EP - 351

JO - Animal Genetics

JF - Animal Genetics

IS - 5

ER -

RFLP and linkage analysis of the porcine casein loci--CASAS1, CASAS2, CASB and CASK

Abstract / Description of output

Keywords / Materials (for Non-textual outputs)

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Cite this