Rhodium-Catalyzed Annulation of Ynamides with Bifunctional Arylboron Reagents

Benoit Gourdet, Mairi E. Rudkin, Hon Wai Lam

Research output: Contribution to journalArticlepeer-review

Abstract

Annulation of ynamides with arylboronic acids or esters containing an electrophilic functional group at the ortho-position proceeds under the action of rhodium catalysis to generate 2-amidoindenols or 2-amidoindenes, usually with good regioselectivity,

Original languageEnglish
Pages (from-to)2554-2557
Number of pages4
JournalOrganic letters
Volume12
Issue number11
DOIs
Publication statusPublished - 4 Jun 2010

Keywords

  • AZA-CLAISEN REARRANGEMENT
  • BOND-FORMING REACTIONS
  • STRAINED ALKENES
  • AQUEOUS-MEDIA
  • REGIOSELECTIVE CARBOCYCLIZATION
  • FACILE ROUTE
  • ALKYNES
  • ACIDS
  • INDENOLS
  • KETONES

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