riboviz: analysis and visualization of ribosome profiling datasets

Oana  Carja; Tongji  Xing; Edward W. J.  Wallace; Joshua B. Plotkin; Premal Shah

doi:https://doi.org/10.1186/s12859-017-1873-8

riboviz: analysis and visualization of ribosome profiling datasets

Oana Carja, Tongji Xing, Edward W. J. Wallace, Joshua B. Plotkin, Premal Shah

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Using high-throughput sequencing to monitor translation in vivo, ribosome profiling can provide critical insights into the dynamics and regulation of protein synthesis in a cell. Since its introduction in 2009, this technique has played a key role in driving biological discovery, and yet it requires a rigorous computational toolkit for widespread adoption.

Original language	English
Journal	BMC Bioinformatics
Volume	18
Issue number	461
DOIs	https://doi.org/10.1186/s12859-017-1873-8
Publication status	Published - 25 Oct 2017

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https://doi.org/10.1186/s12859-017-1873-8

s12859-017-1873-8Final published version, 693 KBLicence: Creative Commons: Attribution (CC-BY)

https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-017-1873-8Licence: Unspecified

MoDATS
Sanguinetti, G.
EU government bodies
5/01/16 → 19/01/18
Project: Research

Cite this

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title = "riboviz: analysis and visualization of ribosome profiling datasets",

abstract = "Using high-throughput sequencing to monitor translation in vivo, ribosome profiling can provide critical insights into the dynamics and regulation of protein synthesis in a cell. Since its introduction in 2009, this technique has played a key role in driving biological discovery, and yet it requires a rigorous computational toolkit for widespread adoption.",

author = "Oana Carja and Tongji Xing and Wallace, {Edward W. J.} and Plotkin, {Joshua B.} and Premal Shah",

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AU - Xing, Tongji

AU - Wallace, Edward W. J.

AU - Plotkin, Joshua B.

AU - Shah, Premal

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AB - Using high-throughput sequencing to monitor translation in vivo, ribosome profiling can provide critical insights into the dynamics and regulation of protein synthesis in a cell. Since its introduction in 2009, this technique has played a key role in driving biological discovery, and yet it requires a rigorous computational toolkit for widespread adoption.

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DO - https://doi.org/10.1186/s12859-017-1873-8

M3 - Article

SN - 1471-2105

VL - 18

JO - BMC Bioinformatics

JF - BMC Bioinformatics

IS - 461

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riboviz: analysis and visualization of ribosome profiling datasets

Abstract / Description of output

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MoDATS

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