riboviz: analysis and visualization of ribosome profiling datasets

Oana Carja, Tongji Xing, Edward W. J. Wallace, Joshua B. Plotkin, Premal Shah

Research output: Contribution to journalArticlepeer-review

Abstract

Using high-throughput sequencing to monitor translation in vivo, ribosome profiling can provide critical insights into the dynamics and regulation of protein synthesis in a cell. Since its introduction in 2009, this technique has played a key role in driving biological discovery, and yet it requires a rigorous computational toolkit for widespread adoption.
Original languageEnglish
JournalBMC Bioinformatics
Volume18
Issue number461
DOIs
Publication statusPublished - 25 Oct 2017

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