Abstract
RKappa is a framework for the development, simulation, and analysis of rule-based models within the mature statistically empowered R environment. It is designed for model editing, parameter identification, simulation, sensitivity analysis, and visualization. The framework is optimized for high-performance computing platforms and facilitates analysis of large-scale systems biology models where knowledge of exact mechanisms is limited and parameter values are uncertain.
Original language | English |
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Title of host publication | Modeling Biomolecular Site Dynamics: Methods and Protocols |
Editors | William S. Hlavacek |
Place of Publication | New York, NY |
Publisher | Springer |
Pages | 363-390 |
Number of pages | 28 |
ISBN (Print) | 978-1-4939-9102-0 |
DOIs | |
Publication status | Published - 2019 |