Role for migratory wild birds in the global spread of avian influenza H5N8

Samantha Lycett; Rogier Bodewes; Anne Pohlmann; Jill Banks; Krisztián Bányai; Maciej F. Boni; Ruth Bouwstra; Andrew C. Breed; Ian H Brown; Hualan Chen; Ádám Dán; Thomas J. DeLiberto; Nguyen Diep; Marius Gilbert; Sarah Hill; Hon S. Ip; Chang Wen Ke; Hiroshi Kida; Mary Lea Killian; Marion P. Koopmans; Jung-Hoon Kwon; Dong-Hun Lee; Joo Yeon Lee; Lu Lu; Isabella Monne; John Pasick; Oliver G. Pybus; Andrew Rambaut; Timothy P. Robinson; Yoshihiro Sakoda; Siamak Zohari; Chang-Seon Song; David E. Swayne; Mia Kim Torchetti; Hsiang-Jung Tsai; Ron A.M. Fouchier; Martin Beer; Mark Woolhouse; Thijs Kuiken

doi:10.1126/science.aaf8852

Role for migratory wild birds in the global spread of avian influenza H5N8

Samantha Lycett, Rogier Bodewes, Anne Pohlmann, Jill Banks, Krisztián Bányai, Maciej F. Boni, Ruth Bouwstra, Andrew C. Breed, Ian H Brown, Hualan Chen, Ádám Dán, Thomas J. DeLiberto, Nguyen Diep, Marius Gilbert, Sarah Hill, Hon S. Ip, Chang Wen Ke, Hiroshi Kida, Mary Lea Killian, Marion P. KoopmansJung-Hoon Kwon, Dong-Hun Lee, Joo Yeon Lee, Lu Lu, Isabella Monne, John Pasick, Oliver G. Pybus, Andrew Rambaut, Timothy P. Robinson, Yoshihiro Sakoda, Siamak Zohari, Chang-Seon Song, David E. Swayne, Mia Kim Torchetti, Hsiang-Jung Tsai, Ron A.M. Fouchier, Martin Beer, Mark Woolhouse, Thijs Kuiken

Research output: Contribution to journal › Article › peer-review

Abstract

Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in 2013/2014, rapidly spread worldwide in 2014/2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the haemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.

Original language	English
Pages (from-to)	213-217
Number of pages	4
Journal	Science
Volume	354
Issue number	6309
DOIs	https://doi.org/10.1126/science.aaf8852
Publication status	Published - 14 Oct 2016

Keywords

AVIAN INFLUENZA
PHYLOGENETIC ANALYSIS
PHYLOGEOGRAPHY
Epidemics/veterinary
MIGRATION

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10.1126/science.aaf8852

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3 Finished

COMPARE: COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe
Woolhouse, M.
EU government bodies
1/12/14 → 30/11/19
Project: Research
Start-up funds for Career Track Fellows
Hume, D.
UK-based charities
1/10/14 → 31/12/17
Project: Research
Innate immunity and endemic diseases in livestock species
Collie, D., Beard, P., Bishop, S., Bronsvoort, M., Burt, D., Fitzgerald, R., Freeman, T., Gally, D., Gill, A., Glass, E., Hocking, P., Hope, J., Hume, D., Kaiser, P., Mabbott, N., McLachlan, G., Morrison, L., Stevens, J., Stevens, M. & Watson, M.
BBSRC
1/04/12 → 31/03/17
Project: Research

Samantha Lycett
- samantha.lycett@ed.ac.uk
- Royal (Dick) School of Veterinary Studies - Senior Lecturer
Person: Academic: Research Active
Mark Woolhouse
- Deanery of Molecular, Genetic and Population Health Sciences - Chair of Infectious Disease Epidemiology
- Global Health Academy
- Usher Institute
- Centre for Global Health Research
Person: Academic: Research Active

Cite this

Lycett, S., Bodewes, R., Pohlmann, A., Banks, J., Bányai, K., Boni, M. F., Bouwstra, R., Breed, A. C., Brown, I. H., Chen, H., Dán, Á., DeLiberto, T. J., Diep, N., Gilbert, M., Hill, S., Ip, H. S., Ke, C. W., Kida, H., Killian, M. L., ... Kuiken, T. (2016). Role for migratory wild birds in the global spread of avian influenza H5N8. Science, 354(6309), 213-217. https://doi.org/10.1126/science.aaf8852

Lycett, Samantha ; Bodewes, Rogier ; Pohlmann, Anne ; Banks, Jill ; Bányai, Krisztián ; Boni, Maciej F. ; Bouwstra, Ruth ; Breed, Andrew C. ; Brown, Ian H ; Chen, Hualan ; Dán, Ádám ; DeLiberto, Thomas J. ; Diep, Nguyen ; Gilbert, Marius ; Hill, Sarah ; Ip, Hon S. ; Ke, Chang Wen ; Kida, Hiroshi ; Killian, Mary Lea ; Koopmans, Marion P. ; Kwon, Jung-Hoon ; Lee, Dong-Hun ; Lee, Joo Yeon ; Lu, Lu ; Monne, Isabella ; Pasick, John ; Pybus, Oliver G. ; Rambaut, Andrew ; Robinson, Timothy P. ; Sakoda, Yoshihiro ; Zohari, Siamak ; Song, Chang-Seon ; Swayne, David E. ; Torchetti, Mia Kim ; Tsai, Hsiang-Jung ; Fouchier, Ron A.M. ; Beer, Martin ; Woolhouse, Mark ; Kuiken, Thijs. / Role for migratory wild birds in the global spread of avian influenza H5N8. In: Science. 2016 ; Vol. 354, No. 6309. pp. 213-217.

@article{bb70bb06abbe44609257788b8db9ac46,

title = "Role for migratory wild birds in the global spread of avian influenza H5N8",

abstract = "Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in 2013/2014, rapidly spread worldwide in 2014/2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the haemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health. ",

keywords = "AVIAN INFLUENZA, PHYLOGENETIC ANALYSIS, PHYLOGEOGRAPHY, Epidemics/veterinary, MIGRATION",

author = "Samantha Lycett and Rogier Bodewes and Anne Pohlmann and Jill Banks and Kriszti{\'a}n B{\'a}nyai and Boni, {Maciej F.} and Ruth Bouwstra and Breed, {Andrew C.} and Brown, {Ian H} and Hualan Chen and {\'A}d{\'a}m D{\'a}n and DeLiberto, {Thomas J.} and Nguyen Diep and Marius Gilbert and Sarah Hill and Ip, {Hon S.} and Ke, {Chang Wen} and Hiroshi Kida and Killian, {Mary Lea} and Koopmans, {Marion P.} and Jung-Hoon Kwon and Dong-Hun Lee and Lee, {Joo Yeon} and Lu Lu and Isabella Monne and John Pasick and Pybus, {Oliver G.} and Andrew Rambaut and Robinson, {Timothy P.} and Yoshihiro Sakoda and Siamak Zohari and Chang-Seon Song and Swayne, {David E.} and Torchetti, {Mia Kim} and Hsiang-Jung Tsai and Fouchier, {Ron A.M.} and Martin Beer and Mark Woolhouse and Thijs Kuiken",

year = "2016",

month = oct,

day = "14",

doi = "10.1126/science.aaf8852",

language = "English",

volume = "354",

pages = "213--217",

journal = "Science",

issn = "0036-8075",

publisher = "AMER ASSOC ADVANCEMENT SCIENCE",

number = "6309",

}

Lycett, S, Bodewes, R, Pohlmann, A, Banks, J, Bányai, K, Boni, MF, Bouwstra, R, Breed, AC, Brown, IH, Chen, H, Dán, Á, DeLiberto, TJ, Diep, N, Gilbert, M, Hill, S, Ip, HS, Ke, CW, Kida, H, Killian, ML, Koopmans, MP, Kwon, J-H, Lee, D-H, Lee, JY, Lu, L, Monne, I, Pasick, J, Pybus, OG, Rambaut, A, Robinson, TP, Sakoda, Y, Zohari, S, Song, C-S, Swayne, DE, Torchetti, MK, Tsai, H-J, Fouchier, RAM, Beer, M, Woolhouse, M & Kuiken, T 2016, 'Role for migratory wild birds in the global spread of avian influenza H5N8', Science, vol. 354, no. 6309, pp. 213-217. https://doi.org/10.1126/science.aaf8852

Role for migratory wild birds in the global spread of avian influenza H5N8. / Lycett, Samantha; Bodewes, Rogier; Pohlmann, Anne; Banks, Jill; Bányai, Krisztián; Boni, Maciej F.; Bouwstra, Ruth; Breed, Andrew C.; Brown, Ian H; Chen, Hualan; Dán, Ádám; DeLiberto, Thomas J.; Diep, Nguyen; Gilbert, Marius; Hill, Sarah; Ip, Hon S.; Ke, Chang Wen; Kida, Hiroshi; Killian, Mary Lea; Koopmans, Marion P.; Kwon, Jung-Hoon; Lee, Dong-Hun; Lee, Joo Yeon; Lu, Lu; Monne, Isabella; Pasick, John; Pybus, Oliver G.; Rambaut, Andrew; Robinson, Timothy P.; Sakoda, Yoshihiro; Zohari, Siamak; Song, Chang-Seon; Swayne, David E.; Torchetti, Mia Kim; Tsai, Hsiang-Jung; Fouchier, Ron A.M.; Beer, Martin; Woolhouse, Mark; Kuiken, Thijs.

In: Science, Vol. 354, No. 6309, 14.10.2016, p. 213-217.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Role for migratory wild birds in the global spread of avian influenza H5N8

AU - Lycett, Samantha

AU - Bodewes, Rogier

AU - Pohlmann, Anne

AU - Banks, Jill

AU - Bányai, Krisztián

AU - Boni, Maciej F.

AU - Bouwstra, Ruth

AU - Breed, Andrew C.

AU - Brown, Ian H

AU - Chen, Hualan

AU - Dán, Ádám

AU - DeLiberto, Thomas J.

AU - Diep, Nguyen

AU - Gilbert, Marius

AU - Hill, Sarah

AU - Ip, Hon S.

AU - Ke, Chang Wen

AU - Kida, Hiroshi

AU - Killian, Mary Lea

AU - Koopmans, Marion P.

AU - Kwon, Jung-Hoon

AU - Lee, Dong-Hun

AU - Lee, Joo Yeon

AU - Lu, Lu

AU - Monne, Isabella

AU - Pasick, John

AU - Pybus, Oliver G.

AU - Rambaut, Andrew

AU - Robinson, Timothy P.

AU - Sakoda, Yoshihiro

AU - Zohari, Siamak

AU - Song, Chang-Seon

AU - Swayne, David E.

AU - Torchetti, Mia Kim

AU - Tsai, Hsiang-Jung

AU - Fouchier, Ron A.M.

AU - Beer, Martin

AU - Woolhouse, Mark

AU - Kuiken, Thijs

PY - 2016/10/14

Y1 - 2016/10/14

N2 - Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in 2013/2014, rapidly spread worldwide in 2014/2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the haemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.

AB - Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in 2013/2014, rapidly spread worldwide in 2014/2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the haemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.

KW - AVIAN INFLUENZA

KW - PHYLOGENETIC ANALYSIS

KW - PHYLOGEOGRAPHY

KW - Epidemics/veterinary

KW - MIGRATION

U2 - 10.1126/science.aaf8852

DO - 10.1126/science.aaf8852

M3 - Article

VL - 354

SP - 213

EP - 217

JO - Science

JF - Science

SN - 0036-8075

IS - 6309

ER -

Role for migratory wild birds in the global spread of avian influenza H5N8

Abstract

Keywords

Access to Document

COMPARE: COllaborative Management Platform for detection and Analyses of (Re-)emerging and foodborne outbreaks in Europe

Start-up funds for Career Track Fellows

Innate immunity and endemic diseases in livestock species

Samantha Lycett

Mark Woolhouse

Cite this