Room Temperature Gold-Catalysed Arylation of Heteroarenes: Complementarity to Palladium Catalysis

Guy Charles Lloyd-jones, Alexander Cresswell

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Tailoring of the pre-catalyst, the oxidant and the arylsilane enables the first room temperature, gold-catalysed, innate C-H arylation of heteroarenes. Regioselectivity is consistently high and, in some cases, distinct from that reported with palladium catalysis. Tolerance to halides and boronic esters, in both the heteroarene and silane partners, provides orthogonality to Suzuki-Miyaura coupling.
Original languageEnglish
JournalChemistry - A European Journal
DOIs
Publication statusPublished - 21 Jun 2016

Fingerprint

Dive into the research topics of 'Room Temperature Gold-Catalysed Arylation of Heteroarenes: Complementarity to Palladium Catalysis'. Together they form a unique fingerprint.

Cite this