S-acylation by the DHHC protein family

J. Greaves, L. H. Chamberlain

Research output: Contribution to journalArticlepeer-review

Abstract

A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.
Original languageEnglish
Pages (from-to)522-524
Number of pages3
JournalBiochemical Society Transactions
Volume38
DOIs
Publication statusPublished - Apr 2010

Keywords

  • Adolescent
  • Adult
  • Aged
  • Aging
  • Alzheimer Disease
  • Amyloid beta-Protein Precursor
  • analysis
  • Brain
  • Child
  • Cognition
  • Cohort Studies
  • Female
  • GENE
  • genes
  • Genetic Markers
  • genetics
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Oxidative Stress
  • physiology
  • Polymorphism,Single Nucleotide
  • psychology
  • Research
  • Research Support

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