S-acylation by the DHHC protein family

J. Greaves; L. H. Chamberlain

doi:10.1042/BST0380522

S-acylation by the DHHC protein family

J. Greaves, L. H. Chamberlain

Deanery of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.

Original language	English
Pages (from-to)	522-524
Number of pages	3
Journal	Biochemical Society Transactions
Volume	38
DOIs	https://doi.org/10.1042/BST0380522
Publication status	Published - Apr 2010

Keywords

Adolescent
Adult
Aged
Aging
Alzheimer Disease
Amyloid beta-Protein Precursor
analysis
Brain
Child
Cognition
Cohort Studies
Female
GENE
genes
Genetic Markers
genetics
Genotype
Humans
Male
Middle Aged
Oxidative Stress
physiology
Polymorphism,Single Nucleotide
psychology
Research
Research Support

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10.1042/BST0380522

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abstract = "A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved. ",

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KW - Adult

KW - Aged

KW - Aging

KW - Alzheimer Disease

KW - Amyloid beta-Protein Precursor

KW - analysis

KW - Brain

KW - Child

KW - Cognition

KW - Cohort Studies

KW - Female

KW - GENE

KW - genes

KW - Genetic Markers

KW - genetics

KW - Genotype

KW - Humans

KW - Male

KW - Middle Aged

KW - Oxidative Stress

KW - physiology

KW - Polymorphism,Single Nucleotide

KW - psychology

KW - Research

KW - Research Support

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DO - 10.1042/BST0380522

M3 - Article

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SP - 522

EP - 524

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

SN - 0300-5127

ER -

S-acylation by the DHHC protein family

Abstract

Keywords

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