Salmonellosis in patients with primary hypogammaglobulinaemia

C L Leen, A D Birch, R P Brettle, P D Welsby, P L Yap

Research output: Contribution to journalArticlepeer-review


Three of 20 patients with primary hypogammaglobulinaemia developed Salmonella gastroenteritis. Two of them who also had low concentrations of serum IgG and pernicious anaemia were clinically septicaemic. Patients with primary hypogammaglobulinaemia have previously been thought not to be more susceptible to Salmonella infection but a combination of low gastric acidity and impaired humoral immunity may predispose them to such infection.
Original languageEnglish
Pages (from-to)241-5
Number of pages5
JournalJournal of Infection
Issue number3
Publication statusPublished - May 1986


  • Adult
  • Agammaglobulinemia
  • Anemia, Pernicious
  • Female
  • Gastroenteritis
  • Humans
  • Immunoglobulin G
  • Male
  • Pregnancy
  • Pregnancy Complications, Hematologic
  • Pregnancy Complications, Infectious
  • Salmonella Infections
  • Salmonella typhimurium


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